Display options
Cite
Singh N, Dogra Y, Saini M, et al. Severe early-onset ovarian hyperstimulation syndrome with liver dysfunction in an IVF segmentation cycle. BMJ Case Rep. 2020;13(1)doi: 10.1136/bcr-2019-233379.
Singh, N., Dogra, Y., Saini, M., & Govindarajan, M. (2020). Severe early-onset ovarian hyperstimulation syndrome with liver dysfunction in an IVF segmentation cycle. BMJ case reports, 13(1), . https://doi.org/10.1136/bcr-2019-233379
Singh, Neeta, et al. "Severe early-onset ovarian hyperstimulation syndrome with liver dysfunction in an IVF segmentation cycle." BMJ case reports vol. 13,1 (2020). doi: https://doi.org/10.1136/bcr-2019-233379
Singh N, Dogra Y, Saini M, Govindarajan M. Severe early-onset ovarian hyperstimulation syndrome with liver dysfunction in an IVF segmentation cycle. BMJ Case Rep. 2020 Jan 26;13(1). doi: 10.1136/bcr-2019-233379. PMID: 31988058; PMCID: PMC7035818.
Copy Download .nbib Format: NLM
Share it on

BMJ Case Rep. 2020 Jan 26;13(1). doi: 10.1136/bcr-2019-233379.

Severe early-onset ovarian hyperstimulation syndrome with liver dysfunction in an IVF segmentation cycle.

BMJ case reports

Neeta Singh, Yogita Dogra, Monika Saini, Matheswari Govindarajan

Affiliations

  1. Obstetrics & Gynecology, All India Institute of Medical Sciences, New Delhi, India.
  2. Obstetrics & Gynecology, All India Institute of Medical Sciences, New Delhi, India [email protected].

PMID: 31988058 PMCID: PMC7035818 DOI: 10.1136/bcr-2019-233379

Abstract

Severe early-onset ovarian hyperstimulation syndrome (OHSS) with deranged liver function tests is an entity that cannot be eliminated wholly even after gonadotropin-releasing hormone (GnRH) agonist trigger without any luteal human chorionic gonadotropin (hCG) rescue in a GnRH antagonist protocol with the freeze-all approach. We describe a case of young polycystic ovary syndrome patient with prior history of severe early-onset OHSS in her last in vitro fertilisation cycle in which she received antagonist protocol followed by blastocyst transfer. Given her history, she was planned for agonist trigger and freeze all approach during the present cycle. Despite segmentation of the cycle without any luteal rescue hCG, she developed early-onset severe OHSS with markedly deranged liver function tests for which she underwent ascitic tapping and remained hospitalised for 8 days. Her symptoms improved with conservative management, and she was discharged satisfactorily. She underwent letrozole based frozen-thawed embryo transfer cycle after 4 months. One good quality blastocyst was transferred, and she conceived in the same cycle.

© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Keywords: pregnancy; reproductive medicine

Conflict of interest statement

Competing interests: None declared.

Substances

MeSH terms

Publication Types