Display options
Cite
Gordon NF, van Rensburg JP, Schwellnus MP. Isoproterenol sensitivity in heat tolerant and relatively heat intolerant men. Eur J Appl Physiol Occup Physiol. 1987;56(5):546-9doi: 10.1007/BF00635368.
Gordon, N. F., van Rensburg, J. P., & Schwellnus, M. P. (1987). Isoproterenol sensitivity in heat tolerant and relatively heat intolerant men. European journal of applied physiology and occupational physiology, 56(5), 546-9. https://doi.org/10.1007/BF00635368
Gordon, N F, et al. "Isoproterenol sensitivity in heat tolerant and relatively heat intolerant men." European journal of applied physiology and occupational physiology vol. 56,5 (1987): 546-9. doi: https://doi.org/10.1007/BF00635368
Gordon NF, van Rensburg JP, Schwellnus MP. Isoproterenol sensitivity in heat tolerant and relatively heat intolerant men. Eur J Appl Physiol Occup Physiol. 1987;56(5):546-9. doi: 10.1007/BF00635368. PMID: 2888649.
Copy Download .nbib Format: NLM
Share it on

Eur J Appl Physiol Occup Physiol. 1987;56(5):546-9. doi: 10.1007/BF00635368.

Isoproterenol sensitivity in heat tolerant and relatively heat intolerant men.

European journal of applied physiology and occupational physiology

N F Gordon, J P van Rensburg, M P Schwellnus

Affiliations

  1. Military Hospital, Pretoria, South Africa.

PMID: 2888649 DOI: 10.1007/BF00635368

Abstract

Recent research has demonstrated that pharmacologic blockade of beta-adrenoceptors predisposes to hyperthermia during prolonged exercise. To investigate the hypothesis that beta-adrenoceptor sensitivity to catecholamines may be an important determinant of exertional heat tolerance, we performed a cross-sectional study comparing the heart rate responses to graded doses of isoproterenol in 6 heat tolerant and 6 relatively heat intolerant men. We observed no significant difference (p greater than 0.1) between the heat tolerant (0.9 +/- 0.68 microgram) and heat intolerant (1.19 +/- 0.61 microgram) subjects in the dose of isoproterenol that produced a 25 beat.min-1 increment in heart rate. Although the possibility of a relationship between beta-adrenoceptor sensitivity and the ability to tolerate exercise in heat cannot be entirely excluded on the basis of these data, our study clearly demonstrates the lack of a correlation between cardiac pacemaker sensitivity to isoproterenol and exertional heat tolerance.

Similar articles

References

  1. JAMA. 1985 Nov 8;254(18):2609-13 - PubMed
  2. Med Sci Sports. 1979 Spring;11(1):60-5 - PubMed
  3. J Appl Physiol (1985). 1985 Mar;58(3):899-906 - PubMed
  4. Arch Intern Med. 1972 Jul;130(1):47-52 - PubMed
  5. Circulation. 1979 Jun;59(6):1158-64 - PubMed
  6. Am J Cardiol. 1985 Apr 26;55(10):68D-73D - PubMed
  7. Arch Intern Med. 1972 Sep;130(3):361-4 - PubMed
  8. Hypertension. 1980 Mar-Apr;2(2):130-8 - PubMed
  9. Eur J Appl Physiol Occup Physiol. 1975 Aug 15;34(3):199-204 - PubMed
  10. J Appl Physiol Respir Environ Exerc Physiol. 1981 Nov;51(5):1232-7 - PubMed

Substances

MeSH terms

Publication Types

LinkOut - more resources