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Nieto A, Hara MR, Quereda V, et al. βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1. Cell Death Differ. 2019;27(4):1200-1213doi: 10.1038/s41418-019-0406-6.
Nieto, A., Hara, M. R., Quereda, V., Grant, W., Saunders, V., Xiao, K., McDonald, P. H., & Duckett, D. R. (2020). βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1. Cell death and differentiation, 27(4), 1200-1213. https://doi.org/10.1038/s41418-019-0406-6
Nieto, Ainhoa, et al. "βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1." Cell death and differentiation vol. 27,4 (2020): 1200-1213. doi: https://doi.org/10.1038/s41418-019-0406-6
Nieto A, Hara MR, Quereda V, Grant W, Saunders V, Xiao K, McDonald PH, Duckett DR. βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1. Cell Death Differ. 2020 Apr;27(4):1200-1213. doi: 10.1038/s41418-019-0406-6. Epub 2019 Sep 10. PMID: 31506606; PMCID: PMC7206116.
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Cell Death Differ. 2020 Apr;27(4):1200-1213. doi: 10.1038/s41418-019-0406-6. Epub 2019 Sep 10.

βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1.

Cell death and differentiation

Ainhoa Nieto, Makoto R Hara, Victor Quereda, Wayne Grant, Vanessa Saunders, Kunhong Xiao, Patricia H McDonald, Derek R Duckett

Affiliations

  1. Department of Cancer Physiology, Moffitt Cancer Center, Tampa, FL, 33612, USA.
  2. Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA.
  3. Novartis Institutes for Biomedical Research, Cambridge, MA, 02139, USA.
  4. Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL, 33612, USA.
  5. Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  6. Department of Cancer Physiology, Moffitt Cancer Center, Tampa, FL, 33612, USA. [email protected].
  7. Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL, 33612, USA. [email protected].

PMID: 31506606 PMCID: PMC7206116 DOI: 10.1038/s41418-019-0406-6

Abstract

Cellular DNA is constantly under threat from internal and external insults, consequently multiple pathways have evolved to maintain chromosomal fidelity. Our previous studies revealed that chronic stress, mediated by continuous stimulation of the β

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