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Wiley

Int J Androl. 1987 Feb;10(1):173-80. doi: 10.1111/j.1365-2605.1987.tb00180.x.

Screening for carcinoma-in-situ of the testis.

International journal of andrology

A Giwercman, J G Berthelsen, J Müller, H von der Maase, N E Skakkebaek

PMID: 2884183 DOI: 10.1111/j.1365-2605.1987.tb00180.x

Abstract

Germ cell neoplasia detected at the preinvasive stage of carcinoma-in-situ (CIS) can be cured by orchidectomy or by localized irradiation of the testis. Therefore, screening for carcinoma-in-situ of the testis has been applied to groups of individuals known to have an increased risk of testicular cancer. A high (5.5%) incidence of CIS was found in the contralateral testis of men with a unilateral cancer of the testis. An increased incidence of CIS was also found among men with a history of cryptorchidism. We recommend routine screening for CIS of the testis in both groups of men. The role of screening for CIS among subfertile men remains to be elucidated.

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