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Hackenberg KAM, Algra A, Al-Shahi Salman R, et al. Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group. Neurocrit Care. 2019;30:87-101doi: 10.1007/s12028-019-00729-0.
Hackenberg, K. A. M., Algra, A., Al-Shahi Salman, R., Frösen, J., Hasan, D., Juvela, S., Langer, D., Meyers, P., Morita, A., Rinkel, G., Etminan, N. (2019). Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group. Neurocritical care, 3087-101. https://doi.org/10.1007/s12028-019-00729-0
Hackenberg, Katharina A M, et al. "Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group." Neurocritical care vol. 30 (2019): 87-101. doi: https://doi.org/10.1007/s12028-019-00729-0
Hackenberg KAM, Algra A, Al-Shahi Salman R, Frösen J, Hasan D, Juvela S, Langer D, Meyers P, Morita A, Rinkel G, Etminan N. Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group. Neurocrit Care. 2019 Jun;30:87-101. doi: 10.1007/s12028-019-00729-0. PMID: 31102238.
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Neurocrit Care. 2019 Jun;30:87-101. doi: 10.1007/s12028-019-00729-0.

Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group.

Neurocritical care

Katharina A M Hackenberg, Ale Algra, Rustam Al-Shahi Salman, Juhana Frösen, David Hasan, Seppo Juvela, David Langer, Philip Meyers, Akio Morita, Gabriel Rinkel, Nima Etminan,

Affiliations

  1. Department of Neurosurgery, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany. [email protected].
  2. Brain Center Rudolph Magnus, Department of Neurology and Neurosurgery, and the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
  3. Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, Edinburgh, UK.
  4. Department of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.
  5. Department of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
  6. Department of Clinical Neurosciences, University of Helsinki, Helsinki, Finland.
  7. Department of Neurosurgery, Hofstra Northwell School of Medicine, and Northwell Health, Lenox-Hill Hospital, New York, NY, USA.
  8. Departments of Neurosurgery and Radiology, Columbia University Medical Center, New York, NY, USA.
  9. Department of Neurological Surgery, Nippon Medical School, Bunkyo-ku, Tokyo, Japan.
  10. Brain Center Rudolf Magnus, Department of Neurology and Neurosurgery and Center of Excellence for Rehabilitation Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  11. Department of Neurosurgery, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany.

PMID: 31102238 DOI: 10.1007/s12028-019-00729-0

Abstract

INTRODUCTION: Variability in usage and definition of data characteristics in previous cohort studies on unruptured intracranial aneurysms (UIA) complicated pooling and proper interpretation of these data. The aim of the National Institute of Health/National Institute of Neurological Disorders and Stroke UIA and Subarachnoid Hemorrhage (SAH) Common Data Elements (CDE) Project was to provide a common structure for data collection in future research on UIA and SAH.

METHODS: This paper describes the development and summarization of the recommendations of the working groups (WGs) on UIAs, which consisted of an international and multidisciplinary panel of cerebrovascular specialists on research and treatment of UIAs. Consensus recommendations were developed by review of previously published CDEs for other neurological diseases and the literature on UIAs. Recommendations for CDEs were classified by priority into 'Core,' 'Supplemental-Highly Recommended,' 'Supplemental,' and 'Exploratory.'

RESULTS: Ninety-one CDEs were compiled; 69 were newly created and 22 were existing CDEs. The CDEs were assigned to eight subcategories and were classified as Core (8), Supplemental-Highly Recommended (23), Supplemental (25), and Exploratory (35) elements. Additionally, the WG developed and agreed on a classification for aneurysm morphology.

CONCLUSION: The proposed CDEs have been distilled from a broad pool of characteristics, measures, or outcomes. The usage of these CDEs will facilitate pooling of data from cohort studies or clinical trials on patients with UIAs.

Keywords: Common data elements; Data standardization; Morphology; Risk factors; Unruptured intracranial aneurysms

References

  1. Stroke. 2001 Feb;32(2):485-91 - PubMed
  2. Lancet Neurol. 2014 Jan;13(1):59-66 - PubMed
  3. Lancet. 2003 Jul 12;362(9378):103-10 - PubMed
  4. Stroke. 2010 Sep;41(9):1969-77 - PubMed
  5. Cerebrovasc Dis. 2013;36(5-6):401-6 - PubMed
  6. AJNR Am J Neuroradiol. 2015 Oct;36(10):1920-6 - PubMed
  7. Lancet Neurol. 2009 Jul;8(7):635-42 - PubMed
  8. Neurology. 2010 May 11;74(19):1494-501 - PubMed
  9. Neurology. 2017 Apr 25;88(17):1600-1606 - PubMed
  10. Stroke. 2013 Apr;44(4):984-7 - PubMed
  11. Stroke. 2013 May;44(5):1256-9 - PubMed
  12. Stroke. 2014 May;45(5):1299-303 - PubMed
  13. Stroke. 2016 Feb;47(2):365-71 - PubMed
  14. Stroke. 2009 Feb;40(2):406-11 - PubMed
  15. Stroke. 2015 Jan;46(1):42-8 - PubMed
  16. Stroke. 2014 Jul;45(7):1958-63 - PubMed
  17. Neurosurgery. 2006 Jun;58(6):1047-53; discussion 1047-53 - PubMed
  18. Neurocrit Care. 2019 Jun;30(Suppl 1):28-35 - PubMed
  19. Stroke. 2016 May;47(5):1213-8 - PubMed
  20. Stroke. 2013 Sep;44(9):2414-21 - PubMed
  21. Lancet Neurol. 2011 Jul;10(7):626-36 - PubMed
  22. N Engl J Med. 2012 Jun 28;366(26):2474-82 - PubMed
  23. Brain. 2005 Oct;128(Pt 10):2421-9 - PubMed
  24. Stroke. 2013 Aug;44(8):2169-73 - PubMed
  25. Stroke. 2005 Dec;36(12):2773-80 - PubMed
  26. J Neurosurg. 2004 Dec;101(6):908-14 - PubMed
  27. J Neurol Neurosurg Psychiatry. 2011 Jan;82(1):4-7 - PubMed
  28. PLoS One. 2015 Jul 06;10(7):e0132494 - PubMed
  29. Stroke. 2009 Jan;40(1):313-6 - PubMed
  30. Stroke. 2016 Apr;47(4):951-7 - PubMed
  31. Neurosurgery. 2017 Sep 1;81(3):432-440 - PubMed
  32. Stroke. 2016 May;47(5):1219-26 - PubMed
  33. J Neurol. 2009 Jan;256(1):45-50 - PubMed

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