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Ishtiak-Ahmed K, Hansen ÅM, Mortensen EL, et al. Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study. Int Arch Occup Environ Health. 2018;92(2):165-173doi: 10.1007/s00420-018-1365-9.
Ishtiak-Ahmed, K., Hansen, �. �. M., Mortensen, E. L., Garde, A. H., Nørgaard, A., Gyntelberg, F., Rod, N. H., Islamoska, S., Lund, R., Phung, T. K. T., Prescott, E., Waldemar, G., & Nabe-Nielsen, K. (2019). Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study. International archives of occupational and environmental health, 92(2), 165-173. https://doi.org/10.1007/s00420-018-1365-9
Ishtiak-Ahmed, Kazi, et al. "Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study." International archives of occupational and environmental health vol. 92,2 (2019): 165-173. doi: https://doi.org/10.1007/s00420-018-1365-9
Ishtiak-Ahmed K, Hansen ÅM, Mortensen EL, Garde AH, Nørgaard A, Gyntelberg F, Rod NH, Islamoska S, Lund R, Phung TKT, Prescott E, Waldemar G, Nabe-Nielsen K. Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study. Int Arch Occup Environ Health. 2019 Feb;92(2):165-173. doi: 10.1007/s00420-018-1365-9. Epub 2018 Oct 28. PMID: 30370497; PMCID: PMC6341042.
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Int Arch Occup Environ Health. 2019 Feb;92(2):165-173. doi: 10.1007/s00420-018-1365-9. Epub 2018 Oct 28.

Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study.

International archives of occupational and environmental health

Kazi Ishtiak-Ahmed, Åse Marie Hansen, Erik Lykke Mortensen, Anne Helene Garde, Ane Nørgaard, Finn Gyntelberg, Naja Hulvej Rod, Sabrina Islamoska, Rikke Lund, Thien Kieu Thi Phung, Eva Prescott, Gunhild Waldemar, Kirsten Nabe-Nielsen

Affiliations

  1. Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark. [email protected].
  2. Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
  3. The National Research Centre for the Working Environment, Lersø Parkallé 105, 2100, Copenhagen, Denmark.
  4. Center for Healthy Aging, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
  5. Department of Neurology, Danish Dementia Research Centre, Rigshospitalet, University of Copenhagen Section 6911, Blegdamsvej 9, 2100, Copenhagen, Denmark.
  6. Department of Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400, Copenhagen, Denmark.

PMID: 30370497 PMCID: PMC6341042 DOI: 10.1007/s00420-018-1365-9

Abstract

PURPOSE: Only a few studies have investigated the impact of negative aspects of social relations on cognitive function, and they have shown mixed results. Conflicts at work are part of the negative aspects of social relations, but the impact of experiencing conflicts at work has not yet been investigated as a risk factor for dementia. Therefore, we investigated whether experiencing prolonged or serious conflicts with a supervisor or colleagues at work was associated with incident dementia in old age.

METHODS: We analyzed data of 6,436 men and women from the third survey of the Copenhagen City Heart Study. At baseline in 1991-1994, the participants reported whether they had ever had a prolonged or serious conflict at work. The participants were followed until 2014. We used Poisson regression to estimate incidence rate ratios (IRR) and their 95% confidence intervals (CI).

RESULTS: After adjusting for potential confounders, the IRR for dementia was 1.53 (95% CI 0.77-3.03) among participants who had reported having prolonged or serious conflicts both with a supervisor and colleagues compared with participants who had never had such conflicts. In separate analyses stratified by sex, the IRRs were 2.14 (95% Cl 0.97-4.71) for men and 0.98 (95% Cl 0.29-3.32) for women.

CONCLUSIONS: Our findings did not support an overall association between experiencing prolonged or serious conflicts at work and incident dementia. However, because of the large differences in the point estimates for men and women, future research could aim at investigating potential sex differences regarding the association between conflicts at work and dementia.

Keywords: Alzheimer’s; Cohort study; Midlife risk factors; Negative aspects of social relations; Psychosocial work factors; Social relations

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