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Xue QF, Dai SL, Yuan SY, et al. Effect of chuanxiongqin (tetrame-thylpyrazine) on microcirculatory perfusion in hamsters and capillary permeability in rats. Proc Chin Acad Med Sci Peking Union Med Coll. 1989;4(4):224-8
Xue, Q. F., Dai, S. L., Yuan, S. Y., Zhu, L. X., Wu, Y. Q., Wang, S. S., Li, C. C., Liu, C. Y., & Wang, Z. Y. (1989). Effect of chuanxiongqin (tetrame-thylpyrazine) on microcirculatory perfusion in hamsters and capillary permeability in rats. Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 4(4), 224-8.
Xue, Q F, et al. "Effect of chuanxiongqin (tetrame-thylpyrazine) on microcirculatory perfusion in hamsters and capillary permeability in rats." Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao vol. 4,4 (1989): 224-8.
Xue QF, Dai SL, Yuan SY, Zhu LX, Wu YQ, Wang SS, Li CC, Liu CY, Wang ZY. Effect of chuanxiongqin (tetrame-thylpyrazine) on microcirculatory perfusion in hamsters and capillary permeability in rats. Proc Chin Acad Med Sci Peking Union Med Coll. 1989;4(4):224-8. PMID: 2631122.
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Proc Chin Acad Med Sci Peking Union Med Coll. 1989;4(4):224-8.

Effect of chuanxiongqin (tetrame-thylpyrazine) on microcirculatory perfusion in hamsters and capillary permeability in rats.

Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao

Q F Xue, S L Dai, S Y Yuan, L X Zhu, Y Q Wu, S S Wang, C C Li, C Y Liu, Z Y Wang

PMID: 2631122

Abstract

The authors continuously observed the effect of Chuanxiongqin on the microcirculation of hamster cheek pouch by use of the Dual-Window Television Automatic Estimating System. It was seen that the caliber of arterioles, the microcirculatory velocity, and blood flow all decreased after local application of noradrenaline and all increased and returned to normal 1 to 30 min after local administration of Chuanxiongqin. Microcirculatory perfusion, however, could not be improved by normal saline or Iluangqi. The effect of Chuanxiongqin on the pulmonary capillary permeability was also investigated in rats. Pulmonary edema was induced in rats by adrenaline administration. Evans blue was injected intravenously and the amount of Evans blue in broncho-alveolar lavage fluid was estimated. It was found that Evans blue was increased in broncho-alveolar fluid of rats with pulmonary edema, and this increase could be lessened by Chuanxiongqin.

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