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Bauml J, Xie SX, Penn C, et al. A Pragmatic Evaluation of the National Cancer Institute Physician Data Query (PDQ)®-Based Brief Counseling on Cancer-Related Fatigue among Patients Undergoing Radiation Therapy. J Palliat Care Med. 2012;2(6)doi: 10.4172/2165-7386.1000125.
Bauml, J., Xie, S. X., Penn, C., Desai, K., Dong, K. W., Bruner, D. W., Vapiwala, N., & Mao, J. J. (2012). A Pragmatic Evaluation of the National Cancer Institute Physician Data Query (PDQ)®-Based Brief Counseling on Cancer-Related Fatigue among Patients Undergoing Radiation Therapy. Journal of palliative care & medicine, 2(6), . https://doi.org/10.4172/2165-7386.1000125
Bauml, Joshua, et al. "A Pragmatic Evaluation of the National Cancer Institute Physician Data Query (PDQ)®-Based Brief Counseling on Cancer-Related Fatigue among Patients Undergoing Radiation Therapy." Journal of palliative care & medicine vol. 2,6 (2012). doi: https://doi.org/10.4172/2165-7386.1000125
Bauml J, Xie SX, Penn C, Desai K, Dong KW, Bruner DW, Vapiwala N, Mao JJ. A Pragmatic Evaluation of the National Cancer Institute Physician Data Query (PDQ)®-Based Brief Counseling on Cancer-Related Fatigue among Patients Undergoing Radiation Therapy. J Palliat Care Med. 2012;2(6). doi: 10.4172/2165-7386.1000125. Epub 2012 Aug 08. PMID: 29479490; PMCID: PMC5824725.
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J Palliat Care Med. 2012;2(6). doi: 10.4172/2165-7386.1000125. Epub 2012 Aug 08.

A Pragmatic Evaluation of the National Cancer Institute Physician Data Query (PDQ)®-Based Brief Counseling on Cancer-Related Fatigue among Patients Undergoing Radiation Therapy.

Journal of palliative care & medicine

Joshua Bauml, Sharon X Xie, Courtney Penn, Krupali Desai, Kimberly W Dong, Deborah Watkins Bruner, Neha Vapiwala, Jun James Mao

Affiliations

  1. Abramson Cancer Center, University of Pennsylvania, 3400 Spruce Street/2 Gates, Philadelphia, Pennsylvania 19104, USA.
  2. Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 3400 Spruce Street/2 Gates, Philadelphia, Pennsylvania 19104, USA.
  3. Department of Family Medicine and Community Health, University of Pennsylvania, 3400 Spruce Street/2 Gates, Philadelphia, Pennsylvania 19104, USA.
  4. Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street/2 Gates, Philadelphia, Pennsylvania 19104, USA.
  5. Woodruff School of Nursing, University of Emory, Georgia 30322, USA.

PMID: 29479490 PMCID: PMC5824725 DOI: 10.4172/2165-7386.1000125

Abstract

PURPOSE: Cancer-Related Fatigue (CRF) negatively affects quality of life among cancer patients. This study seeks to evaluate the outcome and patient receptiveness of a brief counseling program based on National Cancer Institute (NCI) PDQ® information to manage CRF when integrated into Radiation Therapy (RT).

METHODS: We conducted a prospective cohort study among patients undergoing non-palliative RT. Patients with stage I-III tumors and with Karnofsky score 60 or better were given a ten-minute behavioral counseling session during the first two weeks of RT. The Brief Fatigue Inventory (BFI) was administered at baseline/end of RT.

RESULTS: Of 93 patients enrolled, 89% found the counseling useful and practical. By the end of RT, 59% reported increased exercise, 41.6% sought nutrition counseling, 72.7% prioritized daily activities, 74.4% took daytime naps, and 70.5% talked with other cancer patients. Regarding counseling, patients who had received chemotherapy prior to RT had no change in fatigue (-0.2), those who received RT alone had mild increase in fatigue (0.7, p=0.02), and those who received concurrent chemotherapy experienced a substantial increase in fatigue (3.0 to 5.2, p=0.05). Higher baseline fatigue and receipt of chemotherapy were predictive of worsened fatigue in a multivariate model (both p<0.01).

CONCLUSION: Our data suggests that brief behavioral counseling based on NCI guidelines is well accepted by patients showing an uptake in many activities to cope with CRF. Those who receive concurrent chemotherapy and with higher baseline fatigue are at risk for worsening fatigue despite of guideline-based therapy.

Keywords: Adverse effects; Cohort study; Counseling; Fatigue; Neoplasms; Radiotherapy

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