Display options
Cite
Wu TT, Chen Y, Zhou Y, et al. Prognostic Value of Dehydroepiandrosterone Sulfate for Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis. J Am Heart Assoc. 2017;6(5)doi: 10.1161/JAHA.116.004896.
Wu, T. T., Chen, Y., Zhou, Y., Adi, D., Zheng, Y. Y., Liu, F., Ma, Y. T., & Xie, X. (2017). Prognostic Value of Dehydroepiandrosterone Sulfate for Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis. Journal of the American Heart Association, 6(5), . https://doi.org/10.1161/JAHA.116.004896
Wu, Ting-Ting, et al. "Prognostic Value of Dehydroepiandrosterone Sulfate for Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis." Journal of the American Heart Association vol. 6,5 (2017). doi: https://doi.org/10.1161/JAHA.116.004896
Wu TT, Chen Y, Zhou Y, Adi D, Zheng YY, Liu F, Ma YT, Xie X. Prognostic Value of Dehydroepiandrosterone Sulfate for Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis. J Am Heart Assoc. 2017 May 05;6(5). doi: 10.1161/JAHA.116.004896. PMID: 28476876; PMCID: PMC5524067.
Copy Download .nbib Format: NLM
Share it on

J Am Heart Assoc. 2017 May 05;6(5). doi: 10.1161/JAHA.116.004896.

Prognostic Value of Dehydroepiandrosterone Sulfate for Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis.

Journal of the American Heart Association

Ting-Ting Wu, Yuan Chen, Yun Zhou, Dilare Adi, Ying-Ying Zheng, Fen Liu, Yi-Tong Ma, Xiang Xie

Affiliations

  1. Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
  2. Xinjiang Key Laboratory of Cardiovascular Disease Research, Urumqi, China.
  3. Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China [email protected].

PMID: 28476876 PMCID: PMC5524067 DOI: 10.1161/JAHA.116.004896

Abstract

BACKGROUND: The aim of the present study was to estimate the impact of dehydroepiandrosterone sulfate (DHEAS) on the prognosis of patients with cardiovascular disease by performing a systematic review and meta-analysis.

METHODS AND RESULTS: The Embase, PubMed, Web of Science, CNKI, and WanFang databases were searched up to September 5, 2016, to identify eligible studies. The quality of each study was assessed using the Newcastle-Ottawa Scale. The association between DHEAS, either on admission or at discharge, and cardiovascular disease outcomes were reviewed. The overall risk ratio for the effect of DHEAS on all-cause mortality and fatal and nonfatal cardiovascular events was pooled using a fixed-effects or a random-effects model. The publication bias was evaluated using funnel plots. Twenty-five studies were included for systematic review. The follow-up duration ranged from 1 to 19 years. Eighteen studies were included in the meta-analysis. We found that lower DHEAS levels indicated a significant increased risk for all-cause mortality (risk ratio, 1.47; 95% CI, 1.38-1.56 [

CONCLUSIONS: Patients with cardiovascular disease who have lower DHEAS levels may have poorer prognosis than those with higher DHEAS levels.

© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

Keywords: cardiovascular disease; dehydroepiandrosterone sulfate; meta‐analysis; prognosis; sex hormones; systematic review

References

  1. Brain Res Brain Res Rev. 1999 Nov;30(3):264-88 - PubMed
  2. Ann Intern Med. 2006 Aug 1;145(3):176-84 - PubMed
  3. J Clin Endocrinol Metab. 2001 Sep;86(9):4171-7 - PubMed
  4. J Sex Med. 2013 Mar;10(3):661-77 - PubMed
  5. Circulation. 1992 Nov;86(5):1529-35 - PubMed
  6. Clin Endocrinol (Oxf). 2013 Apr;78(4):629-34 - PubMed
  7. Geriatr Gerontol Int. 2011 Apr;11(2):196-203 - PubMed
  8. J Clin Endocrinol Metab. 2013 Sep;98(9):3615-26 - PubMed
  9. Curr Diabetes Rev. 2012 Mar;8(2):131-43 - PubMed
  10. Int J Androl. 2009 Oct;32(5):431-41 - PubMed
  11. Brain Cogn. 2002 Nov;50(2):316-23 - PubMed
  12. J Am Geriatr Soc. 2010 Mar;58(3):421-6 - PubMed
  13. J Intern Med. 1995 May;237(5):465-72 - PubMed
  14. Atherosclerosis. 1989 Oct;79(2-3):197-203 - PubMed
  15. Am J Med Sci. 1996 May;311(5):205-10 - PubMed
  16. J Steroid Biochem Mol Biol. 1993 Jun;45(6):517-24 - PubMed
  17. Psychoneuroendocrinology. 2013 Nov;38(11):2815-9 - PubMed
  18. N Engl J Med. 1986 Dec 11;315(24):1519-24 - PubMed
  19. Arch Intern Med. 2007 Nov 12;167(20):2249-54 - PubMed
  20. Eur J Endocrinol. 2010 Aug;163(2):285-92 - PubMed
  21. Cancer Res. 1986 Jul;46(7):3389-95 - PubMed
  22. Endocrinology. 1999 Feb;140(2):880-7 - PubMed
  23. World J Urol. 2010 Apr;28(2):209-14 - PubMed
  24. Gerontology. 1995;41(6):343-51 - PubMed
  25. J Gerontol A Biol Sci Med Sci. 2006 Sep;61(9):957-62 - PubMed
  26. Psychiatr Danub. 2014 Jun;26(2):187-9 - PubMed
  27. J Endocrinol Invest. 1999;22(10 Suppl):13-8 - PubMed
  28. J Sex Med. 2011 Nov;8(11):2960-82; quiz 2983 - PubMed
  29. Eur J Endocrinol. 2010 May;162(5):919-23 - PubMed
  30. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1268-74 - PubMed
  31. Aging (Milano). 1999 Feb;11(1):30-4 - PubMed
  32. Prog Brain Res. 2010;182:97-148 - PubMed
  33. Mol Cell Biochem. 1994 Feb 23;131(2):99-104 - PubMed
  34. Exp Gerontol. 2012 Dec;47(12):950-7 - PubMed
  35. Circulation. 1994 Jan;89(1):89-93 - PubMed
  36. Rejuvenation Res. 2012 Aug;15(4):349-58 - PubMed
  37. Ann Epidemiol. 2006 Jul;16(7):510-5 - PubMed
  38. J Endocrinol Invest. 2011 Jul-Aug;34(7):557-67 - PubMed
  39. PLoS One. 2013 May 01;8(5):e63224 - PubMed
  40. Stroke. 2013 Jul;44(7):1784-9 - PubMed
  41. Ann N Y Acad Sci. 1994 May 31;719:564-75 - PubMed
  42. Rev Neurosci. 1999;10(2):117-39 - PubMed
  43. Heart. 2010 Apr;96(7):504-9 - PubMed
  44. J Am Coll Cardiol. 2014 Oct 28;64(17):1801-10 - PubMed
  45. Circulation. 1995 Mar 15;91(6):1757-60 - PubMed
  46. Clin Chem. 2008 Jul;54(7):1190-6 - PubMed
  47. Psychosom Med. 2008 Jul;70(6):668-76 - PubMed
  48. Ann N Y Acad Sci. 1995 Dec 29;774:259-70 - PubMed
  49. Aging (Milano). 2000 Aug;12(4):308-14 - PubMed
  50. Metabolism. 2002 Jun;51(6 Suppl 1):40-5 - PubMed
  51. Acta Chir Scand. 1985;151(6):515-9 - PubMed
  52. Best Pract Res Clin Endocrinol Metab. 2011 Apr;25(2):303-19 - PubMed
  53. Eur J Heart Fail. 2010 Sep;12(9):966-73 - PubMed
  54. Clin Chem. 2010 Jul;56(7):1138-47 - PubMed
  55. Best Pract Res Clin Endocrinol Metab. 2011 Apr;25(2):337-53 - PubMed
  56. J Clin Endocrinol Metab. 2010 Nov;95(11):4985-92 - PubMed
  57. Clin Endocrinol (Oxf). 2014 Nov;81(5):775-83 - PubMed
  58. Aging Cell. 2005 Dec;4(6):319-24 - PubMed
  59. Heart. 1998 Oct;80(4):334-7 - PubMed
  60. J Clin Endocrinol Metab. 2010 Sep;95(9):4406-14 - PubMed
  61. Am J Epidemiol. 2001 Jan 1;153(1):79-89 - PubMed
  62. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8167-9 - PubMed
  63. Mol Cell Endocrinol. 1991 Jul;78(3):C113-8 - PubMed
  64. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13410-5 - PubMed

Substances

MeSH terms

Publication Types