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Asian Pac J Trop Med. 2017 Mar;10(3):263-269. doi: 10.1016/j.apjtm.2017.03.005. Epub 2017 Mar 07.

Potential antioxidant properties and hepatoprotective effects of Juniperus phoenicea berries against CCl.

Asian Pacific journal of tropical medicine

Amel Laouar, Fahima Klibet, Ezzeddine Bourogaa, Amel Benamara, Amel Boumendjel, Azzedine Chefrour, Mahfoud Messarah

Affiliations

  1. Laboratory of Biochemistry and Environmental Toxicology, Faculty of Sciences, University of Badji Mokhtar, Annaba 23000, Algeria.
  2. Department of Biochemistry and Biological Cellular and Molecular, Faculty of Sciences, University of Mentouri, BP 25000 Constantine, Algeria.
  3. Laboratory of Animal Ecophysiology, Faculty of Sciences, Sfax, Soukra Road-Km 3.5, BP 802, 3018 Sfax, Tunisia.
  4. Department of Applied Biology, Faculty of Natural Sciences and Life, University of Larbi Tebessi, Tebessa 12000, Algeria.
  5. Laboratory of Pharmaceutical Preparations for Hospital Use, Department of Pharmacy, Faculty of Medicine, University of Badji, Mokhtar-Annaba 23000, Algeria; Department of Biology, Faculty of Natural Sciences and Life, University of Mohamed Cherif Mesaadia, Souk Ahras 41000, Algeria.
  6. Laboratory of Biochemistry and Environmental Toxicology, Faculty of Sciences, University of Badji Mokhtar, Annaba 23000, Algeria. Electronic address: [email protected].

PMID: 28442109 DOI: 10.1016/j.apjtm.2017.03.005

Abstract

OBJECTIVE: To investigate the antioxidant and hepatoprotective properties of Juniperus phoenicea (J. phoenicea) berries against CCl

METHODS: Hepatotoxicity was induced in albino Wistar rats by single dose of CCl

RESULTS: Obtained results revealed that administration of CCl

CONCLUSIONS: The results of the present investigation indicate that J. Phoenicea possesses hepatoprotective activity and this effect was may be due to its antioxidant properties.

Copyright © 2017 Hainan Medical University. Production and hosting by Elsevier B.V. All rights reserved.

Keywords: Antioxidant; Biochemical parameters; Hepatoprotective; Juniperus phoenicea; Lipid peroxidation; Oxidative stress

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