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Leshchiniuk II, Konovalova EO, Kvitchataia AI, et al. Vliianie vestibuloprotektorov na sistemu tsiklicheskikh nukleotidov pri modelirovanii bolezni dvizheniia. [The effect of vestibuloprotectors on the cyclic nucleotide system in experimental motion sickness]. Patol Fiziol Eksp Ter. 1989;(1):26-8
Leshchiniuk, I. I., Konovalova, E. O., Kvitchataia, A. I., Shamraĭ, V. G., & Bobkov, I. u. G. (1989). Vliianie vestibuloprotektorov na sistemu tsiklicheskikh nukleotidov pri modelirovanii bolezni dvizheniia. [The effect of vestibuloprotectors on the cyclic nucleotide system in experimental motion sickness]. Patologicheskaia fiziologiia i eksperimental'naia terapiia, (1), 26-8.
Leshchiniuk, I I, et al. "Vliianie vestibuloprotektorov na sistemu tsiklicheskikh nukleotidov pri modelirovanii bolezni dvizheniia." [The effect of vestibuloprotectors on the cyclic nucleotide system in experimental motion sickness]. Patologicheskaia fiziologiia i eksperimental'naia terapiia vol. ,1 (1989): 26-8.
Leshchiniuk II, Konovalova EO, Kvitchataia AI, Shamraĭ VG, Bobkov IuG. Vliianie vestibuloprotektorov na sistemu tsiklicheskikh nukleotidov pri modelirovanii bolezni dvizheniia. [The effect of vestibuloprotectors on the cyclic nucleotide system in experimental motion sickness]. Patol Fiziol Eksp Ter. 1989 Jan-Feb;(1):26-8. Russian. PMID: 2785671.
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Patol Fiziol Eksp Ter. 1989 Jan-Feb;(1):26-8.

[The effect of vestibuloprotectors on the cyclic nucleotide system in experimental motion sickness].

Patologicheskaia fiziologiia i eksperimental'naia terapiia

[Article in Russian]
I I Leshchiniuk, E O Konovalova, A I Kvitchataia, V G Shamraĭ, Iu G Bobkov

PMID: 2785671

Abstract

Changes in the blood plasma cyclic nucleotide (cAMP and cGMP) level under the effect of vestibuloprotectors: bemytil and etoxibemytil were studied in rats with experimental motion sickness. It is established that rotation causes increase in the cAMP level and decrease in the cGMP level. The effect of the vestibuloprotectors is determined by the dose of the drug and is aimed first of all at maintaining a stable cAMP level in vestibular exertion. Under conditions of this experiment etoxibemytil was more effective than bemytil.

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