Display options
Cite
Li S, Hafeez A, Noorulla F, et al. Preconditioning in neuroprotection: From hypoxia to ischemia. Prog Neurobiol. 2017;157:79-91doi: 10.1016/j.pneurobio.2017.01.001.
Li, S., Hafeez, A., Noorulla, F., Geng, X., Shao, G., Ren, C., Lu, G., Zhao, H., Ding, Y., & Ji, X. (2017). Preconditioning in neuroprotection: From hypoxia to ischemia. Progress in neurobiology, 15779-91. https://doi.org/10.1016/j.pneurobio.2017.01.001
Li, Sijie, et al. "Preconditioning in neuroprotection: From hypoxia to ischemia." Progress in neurobiology vol. 157 (2017): 79-91. doi: https://doi.org/10.1016/j.pneurobio.2017.01.001
Li S, Hafeez A, Noorulla F, Geng X, Shao G, Ren C, Lu G, Zhao H, Ding Y, Ji X. Preconditioning in neuroprotection: From hypoxia to ischemia. Prog Neurobiol. 2017 Oct;157:79-91. doi: 10.1016/j.pneurobio.2017.01.001. Epub 2017 Jan 18. PMID: 28110083; PMCID: PMC5515698.
Copy Download .nbib Format: NLM
Share it on

Prog Neurobiol. 2017 Oct;157:79-91. doi: 10.1016/j.pneurobio.2017.01.001. Epub 2017 Jan 18.

Preconditioning in neuroprotection: From hypoxia to ischemia.

Progress in neurobiology

Sijie Li, Adam Hafeez, Fatima Noorulla, Xiaokun Geng, Guo Shao, Changhong Ren, Guowei Lu, Heng Zhao, Yuchuan Ding, Xunming Ji

Affiliations

  1. Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuan Wu Hospital, Capital Medical University, Beijing, China; National Clinical Research Center for Geriatric Disorders, Beijing, China.
  2. Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI, USA.
  3. Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI, USA; Department of Neurology, Luhe Hospital, Capital Medical University, Beijing, China.
  4. Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuan Wu Hospital, Capital Medical University, Beijing, China.
  5. Department of Neurosurgery, Stanford University, CA, USA.
  6. Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuan Wu Hospital, Capital Medical University, Beijing, China; Department of Neurological Surgery, Wayne State University School of Medicine, Detroit, MI, USA.
  7. Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuan Wu Hospital, Capital Medical University, Beijing, China; National Clinical Research Center for Geriatric Disorders, Beijing, China. Electronic address: [email protected].

PMID: 28110083 PMCID: PMC5515698 DOI: 10.1016/j.pneurobio.2017.01.001

Abstract

Sublethal hypoxic or ischemic events can improve the tolerance of tissues, organs, and even organisms from subsequent lethal injury caused by hypoxia or ischemia. This phenomenon has been termed hypoxic or ischemic preconditioning (HPC or IPC) and is well established in the heart and the brain. This review aims to discuss HPC and IPC with respect to their historical development and advancements in our understanding of the neurochemical basis for their neuroprotective role. Through decades of collaborative research and studies of HPC and IPC in other organ systems, our understanding of HPC and IPC-induced neuroprotection has expanded to include: early- (phosphorylation targets, transporter regulation, interfering RNA) and late- (regulation of genes like EPO, VEGF, and iNOS) phase changes, regulators of programmed cell death, members of metabolic pathways, receptor modulators, and many other novel targets. The rapid acceleration in our understanding of HPC and IPC will help facilitate transition into the clinical setting.

Copyright © 2017. Published by Elsevier Ltd.

Keywords: Endogenous protection; Molecular mechanisms; Preconditioning; Stroke; Tissue tolerance

References

  1. Neurochem Res. 1999 May;24(5):625-8 - PubMed
  2. Chest. 1999 Jun;115(6):1672-7 - PubMed
  3. J Cereb Blood Flow Metab. 1999 Jul;19(7):757-61 - PubMed
  4. J Neurosci. 1999 Aug 15;19(16):6818-24 - PubMed
  5. Respir Physiol. 1999 Aug 3;116(2-3):95-103 - PubMed
  6. Biol Signals Recept. 1999 Jul-Oct;8(4-5):256-60 - PubMed
  7. Comp Biochem Physiol A Mol Integr Physiol. 1999 Jul;123(3):221-34 - PubMed
  8. Neurosci Lett. 1999 Oct 15;274(1):45-8 - PubMed
  9. J Cereb Blood Flow Metab. 1999 Oct;19(10):1126-35 - PubMed
  10. J Cereb Blood Flow Metab. 1999 Nov;19(11):1229-37 - PubMed
  11. Eur J Neurosci. 1999 Dec;11(12):4159-70 - PubMed
  12. Comp Biochem Physiol A Mol Integr Physiol. 1999 Sep;124(1):1-17 - PubMed
  13. Blood. 2000 Jan 1;95(1):189-97 - PubMed
  14. Eur J Cardiothorac Surg. 1999 Dec;16(6):639-46 - PubMed
  15. Brain Res Dev Brain Res. 2000 Jan 3;119(1):139-53 - PubMed
  16. Ann Thorac Surg. 2000 Jan;69(1):237-42 - PubMed
  17. J Neurophysiol. 2000 Apr;83(4):1830-9 - PubMed
  18. J Immunol. 2000 Jul 15;165(2):1013-21 - PubMed
  19. Free Radic Biol Med. 2000 May 15;28(10):1456-62 - PubMed
  20. Comp Biochem Physiol A Mol Integr Physiol. 2000 Aug;126(4):481-90 - PubMed
  21. Brain Res Mol Brain Res. 2000 Sep 30;81(1-2):29-42 - PubMed
  22. J Neurosci. 2000 Oct 1;20(19):7183-92 - PubMed
  23. Nature. 2000 Sep 21;407(6802):317-8 - PubMed
  24. Hepatology. 2001 Jan;33(1):100-13 - PubMed
  25. Trends Pharmacol Sci. 2000 Nov;21(11):423-4 - PubMed
  26. Chin Med J (Engl). 1998 Oct;111(10):870-3 - PubMed
  27. Brain Res. 2001 Mar 2;893(1-2):301-9 - PubMed
  28. J Cereb Blood Flow Metab. 2001 Sep;21(9):1105-14 - PubMed
  29. J Heart Lung Transplant. 2001 Sep;20(9):985-95 - PubMed
  30. Neurosci Lett. 2001 Oct 12;312(1):21-4 - PubMed
  31. Cell. 2001 Oct 5;107(1):43-54 - PubMed
  32. Science. 2001 Nov 9;294(5545):1337-40 - PubMed
  33. Cardiovasc Res. 2002 Jan;53(1):175-80 - PubMed
  34. Circulation. 2001 Dec 18;104(25):3158-67 - PubMed
  35. Intensive Care Med. 2001 Dec;27(12):1835-41 - PubMed
  36. Development. 2002 Jan;129(2):505-16 - PubMed
  37. Acta Haematol. 2001;106(4):148-56 - PubMed
  38. J Cereb Blood Flow Metab. 2002 Apr;22(4):393-403 - PubMed
  39. J Vasc Surg. 2002 Jun;35(6):1264-73 - PubMed
  40. Nat Med. 2002 Jul;8(7):702-10 - PubMed
  41. Hunan Yi Ke Da Xue Xue Bao. 1999;24(4):319-21 - PubMed
  42. Hunan Yi Ke Da Xue Xue Bao. 1999;24(4):357-9 - PubMed
  43. Hepatology. 2002 Sep;36(3):562-72 - PubMed
  44. Shock. 2002 Nov;18(5):476-80 - PubMed
  45. J Neurol. 2002 Nov;249(11):1503-11 - PubMed
  46. J Cereb Blood Flow Metab. 2002 Nov;22(11):1283-96 - PubMed
  47. J Neurosci. 2002 Dec 1;22(23):10291-301 - PubMed
  48. Circulation. 2002 Dec 3;106(23):2881-3 - PubMed
  49. J Appl Physiol (1985). 2003 Jan;94(1):358-74 - PubMed
  50. Hunan Yi Ke Da Xue Xue Bao. 2001 Feb 28;26(1):51-4 - PubMed
  51. Hunan Yi Ke Da Xue Xue Bao. 2002 Feb 28;27(1):43-5 - PubMed
  52. J Surg Res. 2003 Jan;109(1):24-30 - PubMed
  53. Trends Neurosci. 2003 May;26(5):248-54 - PubMed
  54. Stroke. 2003 Aug;34(8):1981-6 - PubMed
  55. J Am Coll Cardiol. 2003 Aug 6;42(3):437-45 - PubMed
  56. Zhonghua Wai Ke Za Zhi. 2003 Jul;41(7):545-7 - PubMed
  57. Annu Rev Physiol. 1992;54:601-18 - PubMed
  58. Acta Paediatr. 1958 May;47(3):217-37 - PubMed
  59. J Am Coll Cardiol. 2003 Sep 17;42(6):998-1003 - PubMed
  60. Biochem Biophys Res Commun. 1992 Apr 30;184(2):1056-9 - PubMed
  61. J Physiol. 1959 Dec;149:346-73 - PubMed
  62. Int Anesthesiol Clin. 1964 Feb;2:251-69 - PubMed
  63. Am J Physiol. 1964 Aug;207:452-6 - PubMed
  64. J Clin Invest. 2004 Jan;113(1):14-8 - PubMed
  65. Stroke. 2004 Mar;35(3):616-21 - PubMed
  66. J Immunol. 1992 Aug 15;149(4):1388-94 - PubMed
  67. Heart. 2004 Apr;90(4):425-30 - PubMed
  68. J Neurochem. 2004 Apr;89(1):157-67 - PubMed
  69. Expert Opin Ther Targets. 2004 Apr;8(2):125-39 - PubMed
  70. J Nucl Med. 2004 May;45(5):725-9 - PubMed
  71. Respiration. 1992;59 Suppl 2:24-9 - PubMed
  72. J Neurosci. 2004 Jun 23;24(25):5651-8 - PubMed
  73. Respir Physiol Neurobiol. 2004 Aug 12;141(3):215-28 - PubMed
  74. Respir Physiol Neurobiol. 2004 Aug 12;141(3):285-96 - PubMed
  75. Respir Physiol Neurobiol. 2004 Aug 12;141(3):345-56 - PubMed
  76. J Exp Biol. 2004 Aug;207(Pt 18):3233-42 - PubMed
  77. Physiol Genomics. 2004 Sep 16;19(1):143-50 - PubMed
  78. Cerebrovasc Dis. 2004;18(4):304-11 - PubMed
  79. J Neurosci Res. 2005 Mar 15;79(6):816-24 - PubMed
  80. Semin Perinatol. 2004 Dec;28(6):389-95 - PubMed
  81. NeuroRx. 2004 Jan;1(1):26-35 - PubMed
  82. Neurosci Lett. 2005 Apr 4;377(3):206-11 - PubMed
  83. Transplant Proc. 2005 Jan-Feb;37(1):377-8 - PubMed
  84. Neurosci Lett. 2005 Aug 12-19;384(1-2):1-6 - PubMed
  85. Mol Neurobiol. 2005;31(1-3):255-71 - PubMed
  86. Transplantation. 2005 Jun 27;79(12):1691-5 - PubMed
  87. Neurosci Res. 2005 Sep;53(1):39-47 - PubMed
  88. Neurosignals. 2005;14(5):255-61 - PubMed
  89. J Neurosci Res. 2006 Jan;83(1):19-27 - PubMed
  90. Curr Pharm Des. 2006;12(6):739-57 - PubMed
  91. J Zhejiang Univ Sci B. 2006 May;7(5):331-41 - PubMed
  92. Nat Rev Neurosci. 2006 Jun;7(6):437-48 - PubMed
  93. J Cereb Blood Flow Metab. 2006 Sep;26(9):1114-21 - PubMed
  94. Biochem J. 1927;21(5):1068-75 - PubMed
  95. Heart. 2006 Oct;92(10):1506-11 - PubMed
  96. Neurosci Lett. 2006 Aug 14;404(1-2):72-7 - PubMed
  97. Comp Biochem Physiol A Mol Integr Physiol. 2007 Jun;147(2):263-76 - PubMed
  98. Annu Rev Physiol. 2007;69:113-43 - PubMed
  99. Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H751-7 - PubMed
  100. J Biol Chem. 1991 Jun 25;266(18):11947-54 - PubMed
  101. J Neurosurg Anesthesiol. 2007 Jan;19(1):18-24 - PubMed
  102. Neurobiol Dis. 2007 Apr;26(1):243-52 - PubMed
  103. Crit Rev Oncol Hematol. 2007 Nov;64(2):159-71 - PubMed
  104. Pediatr Res. 2007 Apr;61(4):444-50 - PubMed
  105. Neurosurg Focus. 2007 May 15;22(5):E13 - PubMed
  106. Neurosci Lett. 2007 Aug 23;423(3):219-24 - PubMed
  107. Zhonghua Xin Xue Guan Bing Za Zhi. 2007 Aug;35(8):750-6 - PubMed
  108. Brain Res. 1991 Oct 11;561(2):203-11 - PubMed
  109. J Neurol Sci. 2008 May 15;268(1-2):18-27 - PubMed
  110. Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H901-8 - PubMed
  111. J Neurosci Res. 2008 Jun;86(8):1659-69 - PubMed
  112. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4892-7 - PubMed
  113. Brain Res. 2008 May 19;1210:223-9 - PubMed
  114. Sheng Li Xue Bao. 2008 Apr 25;60(2):249-53 - PubMed
  115. Brain Res. 2008 May 23;1211:22-9 - PubMed
  116. J Stroke Cerebrovasc Dis. 2008 Sep;17(5):257-62 - PubMed
  117. Brain Res Rev. 2009 Apr;60(1):202-13 - PubMed
  118. J Exp Biol. 1991 Sep;159:203-15 - PubMed
  119. Acta Pharmacol Sin. 2009 Aug;30(8):1071-80 - PubMed
  120. Annu Rev Genet. 2009;43:95-118 - PubMed
  121. Transpl Int. 2010 Jan;23(1):80-9 - PubMed
  122. J Neurosurg Anesthesiol. 2010 Jan;22(1):46-52 - PubMed
  123. Am J Physiol. 1947 Jun;149(3):565-88 - PubMed
  124. Cell. 1991 May 17;65(4):663-75 - PubMed
  125. Vasc Endovascular Surg. 2010 Aug;44(6):434-9 - PubMed
  126. J Neurochem. 2010 Aug;114(3):897-908 - PubMed
  127. J Cereb Blood Flow Metab. 2011 Feb;31(2):467-75 - PubMed
  128. J Surg Res. 2010 Nov;164(1):e83-9 - PubMed
  129. Bull Johns Hopkins Hosp. 1946 Jul;79:70-89 - PubMed
  130. Nitric Oxide. 2011 Aug 1;25(2):70-80 - PubMed
  131. J Neurochem. 2011 Apr;117(2):346-56 - PubMed
  132. Neurosci Lett. 2011 Jul 12;498(3):227-31 - PubMed
  133. Neurochem Int. 2011 Aug;59(1):65-72 - PubMed
  134. Nat Rev Cardiol. 2011 Jun 21;8(11):619-29 - PubMed
  135. Neurorehabil Neural Repair. 2012 Feb;26(2):163-72 - PubMed
  136. J Hypertens. 2011 Nov;29(11):2265-72 - PubMed
  137. Mutagenesis. 2012 Sep;27(5):573-80 - PubMed
  138. Neurology. 2012 Oct 30;79(18):1853-61 - PubMed
  139. Circ Res. 1990 Apr;66(4):913-31 - PubMed
  140. Pharmacol Res. 2013 Apr;70(1):116-25 - PubMed
  141. Brain Res. 2013 Mar 29;1503:78-88 - PubMed
  142. Mol Neurobiol. 2013 Aug;48(1):109-19 - PubMed
  143. Gerontology. 2013;59(4):316-23 - PubMed
  144. Neurotherapeutics. 2013 Oct;10(4):789-97 - PubMed
  145. J Neurosci Res. 2013 Oct;91(10):1349-62 - PubMed
  146. BMC Genomics. 2013 Sep 18;14:631 - PubMed
  147. Stroke. 2014 Jan;45(1):159-67 - PubMed
  148. Am J Respir Crit Care Med. 2014 Jan 1;189(1):57-65 - PubMed
  149. Neurology. 2014 Jan 14;82(2):104-13 - PubMed
  150. Comp Biochem Physiol A Mol Integr Physiol. 2014 Mar;169:51-9 - PubMed
  151. Prog Neurobiol. 2014 Mar;114:58-83 - PubMed
  152. Brain Res Bull. 2014 Apr;103:66-71 - PubMed
  153. Amino Acids. 2014 Jun;46(6):1537-45 - PubMed
  154. Circ Res. 2014 May 9;114(10):1601-10 - PubMed
  155. J Surg Res. 2014 Jun 15;189(2):198-206 - PubMed
  156. Acta Histochem. 2014 Jun;116(5):949-57 - PubMed
  157. PLoS One. 2014 Jun 10;9(6):e99526 - PubMed
  158. Neuroscience. 2014 Sep 26;277:111-22 - PubMed
  159. Int J Dev Neurosci. 2014 Oct;37:69-75 - PubMed
  160. J Neuropathol Exp Neurol. 2014 Oct;73(10):975-86 - PubMed
  161. Cell Transplant. 2015;24(9):1901-11 - PubMed
  162. J Biol Chem. 2014 Nov 7;289(45):31349-60 - PubMed
  163. JACC Cardiovasc Interv. 2015 Jan;8(1 Pt B):178-188 - PubMed
  164. Folia Neuropathol. 2014;52(3):270-84 - PubMed
  165. J Mol Neurosci. 2015 Apr;55(4):923-30 - PubMed
  166. Front Immunol. 2014 Oct 22;5:523 - PubMed
  167. Acta Neurobiol Exp (Wars). 2014;74(4):396-404 - PubMed
  168. Mol Pharmacol. 1989 Jul;36(1):106-12 - PubMed
  169. Chem Biol Interact. 2015 May 5;232:21-9 - PubMed
  170. J Surg Res. 2015 Jun 1;196(1):190-9 - PubMed
  171. Int J Mol Med. 2015 Jun;35(6):1537-44 - PubMed
  172. Int J Dev Neurosci. 2015 Aug;44:6-13 - PubMed
  173. Chem Biol Interact. 2015 Jul 5;236:57-66 - PubMed
  174. Neurotherapeutics. 2015 Jul;12(3):667-77 - PubMed
  175. JAMA. 2015 Jun 2;313(21):2133-41 - PubMed
  176. Neural Regen Res. 2015 Apr;10(4):542-3 - PubMed
  177. CNS Neurosci Ther. 2016 Jan;22(1):43-52 - PubMed
  178. Nat Rev Neurol. 2015 Dec;11(12):698-710 - PubMed
  179. Neural Regen Res. 2015 Sep;10(9):1471-6 - PubMed
  180. Acta Histochem. 2016 Mar;118(2):80-9 - PubMed
  181. Acta Cir Bras. 2016 Jan;31(1):1-7 - PubMed
  182. Respir Physiol. 1989 Oct;78(1):31-43 - PubMed
  183. Circ Res. 1989 Mar;64(3):437-48 - PubMed
  184. Brain Circ. 2015 Jul-Dec;1(2):133-139 - PubMed
  185. J Appl Physiol (1985). 1987 Aug;63(2):546-53 - PubMed
  186. Brain Res. 1986 May 28;374(2):244-8 - PubMed
  187. Circulation. 1986 Nov;74(5):1124-36 - PubMed
  188. Curr Ther Res Clin Exp. 1972 Jul;14(7):343-8 - PubMed
  189. Biochem J. 1995 Nov 15;312 ( Pt 1):163-7 - PubMed
  190. Circulation. 1993 Mar;87(3):893-9 - PubMed
  191. J Cereb Blood Flow Metab. 1994 Nov;14(6):887-91 - PubMed
  192. J Am Coll Cardiol. 1994 Oct;24(4):1133-42 - PubMed
  193. J Cereb Blood Flow Metab. 1994 Mar;14(2):193-205 - PubMed
  194. J Appl Physiol (1985). 1993 Dec;75(6):2570-9 - PubMed
  195. Stroke. 1994 Mar;25(3):715-7 - PubMed
  196. Mol Chem Neuropathol. 1994 Jan;21(1):1-11 - PubMed
  197. J Cereb Blood Flow Metab. 1993 Jul;13(4):728-32 - PubMed
  198. J Appl Physiol (1985). 1993 Feb;74(2):905-10 - PubMed
  199. Can J Physiol Pharmacol. 1996 Mar;74(3):331-6 - PubMed
  200. J Lab Clin Med. 1996 Sep;128(3):251-8 - PubMed
  201. J Neurosci. 1996 Oct 1;16(19):6236-45 - PubMed
  202. Circulation. 1996 Nov 1;94(9):2193-200 - PubMed
  203. Comp Biochem Physiol B Biochem Mol Biol. 1996 Jan;113(1):37-43 - PubMed
  204. Neuroscience. 1996 Dec;75(3):687-94 - PubMed
  205. Science. 1997 Jan 31;275(5300):661-5 - PubMed
  206. J Cereb Blood Flow Metab. 1997 Feb;17(2):175-82 - PubMed
  207. Neurology. 1997 Feb;48(2):306-11 - PubMed
  208. J Cereb Blood Flow Metab. 1997 Mar;17(3):257-64 - PubMed
  209. Biol Chem. 1997 Jul;378(7):609-16 - PubMed
  210. J Appl Physiol. 1976 May;40(5):658-67 - PubMed
  211. Cell. 1997 Oct 17;91(2):231-41 - PubMed
  212. Am J Physiol. 1997 Oct;273(4 Pt 2):H1707-12 - PubMed
  213. Genes Dev. 1998 Jan 15;12(2):149-62 - PubMed
  214. J Biol Chem. 1998 Feb 6;273(6):3320-6 - PubMed
  215. J Neurosci. 1998 Apr 15;18(8):2933-43 - PubMed
  216. Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4635-40 - PubMed
  217. J Cereb Blood Flow Metab. 1998 Aug;18(8):887-95 - PubMed
  218. Eur J Pharmacol. 1998 Jun 26;351(3):313-22 - PubMed
  219. Blood. 1998 Oct 1;92(7):2260-8 - PubMed
  220. Neurosci Lett. 1998 Sep 25;254(2):117-20 - PubMed
  221. Am J Physiol. 1998 Nov;275(5 Pt 2):H1542-7 - PubMed
  222. Gene Expr. 1998;7(3):205-13 - PubMed
  223. FASEB J. 1999 Jan;13(1):9-22 - PubMed
  224. J Neurosci. 1999 Jan 15;19(2):664-73 - PubMed
  225. J Am Coll Cardiol. 1999 Feb;33(2):556-64 - PubMed

MeSH terms

Publication Types

Grant support