Kardiologiia. 1977 Jul;17(7):112-6.

[Myocardial function in patients with congenital pulmonary valve stenosis].

Kardiologiia

[Article in Russian]
E N Meshalkin, G F Arkhipova, G G Chasovskikh, M P Odintsova, V M Solov'ev

PMID: 200784

Abstract

The studies of metabolism and morphology of the myocardium, and of ECG parameters in 72 patients with valvular pulmonary stenosis conducted with biopsy and autopsy material has demonstrated that while the workload on the right ventricle grows and the severity of the pathological process increases, the oxidative capacity of the myocardium also increase, the indices of its energy supply decrease, the degree of myocytes hypertrophy grows, and the number of mitochondria and the coefficient of their energy efficacy decrease. A correlation was established between the degree of these changes and the severity of electrocardiographic signs of hypertrophy and disorders in the repolarization process in the right ventricle.

Substances

• Adenine Nucleotides
• Phosphates
• Phosphocreatine
• Succinate Dehydrogenase
• Electron Transport Complex IV

MeSH terms

• Adenine Nucleotides / metabolism
• Electron Transport Complex IV / metabolism
• Glycolysis
• Humans
• Microscopy, Electron
• Mitochondria, Heart / metabolism
• Myocardium / ultrastructure
• Oxygen Consumption
• Phosphates / metabolism
• Phosphocreatine / metabolism
• Pulmonary Valve Stenosis / congenital
• Pulmonary Valve Stenosis / pathology
• Succinate Dehydrogenase / metabolism

Publication Types

• English Abstract
• Journal Article

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