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Hepatogastroenterology. 1985 Oct;32(5):232-4.

Orcein-positive material in Kupffer cells from the liver.

Hepato-gastroenterology

C Uehara, M Sakurai, H Ishizu, N Mitsutani, T Koizumi

PMID: 2416662

Abstract

Orcein-positive material in Kupffer cells obtained from 1,377 needle biopsies of the liver was studied for hepatitis B surface antigen (HBsAg). Fifty-five (57%) out of 96 cases with orcein-positive Kupffer cells had acute hepatitis, and 46 (84%) of these 55 were in the late stage of their illness. Orcein-positive material in Kupffer cells was not associated with HBsAg as evaluated by the immune peroxidase method. Orcein-positive material in Kupffer cells appears to consist mainly of lipofuscins developing in the course of acute hepatitis.

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