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Ann Trop Paediatr. 1987 Jun;7(2):145-8. doi: 10.1080/02724936.1987.11748493.

Neurofibromatosis in Nigerian children.

Annals of tropical paediatrics

S A Ademiluyi, G T Ijaduola

PMID: 2441653 DOI: 10.1080/02724936.1987.11748493

Abstract

A study of 14 children with multiple neurofibromatosis (Von Recklinghausen's disease) seen at the Lagos University Teaching Hospital within a 6-year period (1979-85) has been carried out. Eight were boys while six were girls. The youngest was 3 months old. The café-au-lait spots observed in all these children showed poor colour contrast, thus making it not easily discernible in infancy and early diagnosis difficult. They are therefore better called "café-sans-lait" or "blackish brown" spots in the African. Hyperpigmented patches were observed in eight children and multiple grotesque soft tissue swellings in ten others. Prolonged follow-up is mandatory in these patients in order to give them a better quality of life.

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