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Paschke R, Schwedes U, Kühnle H, et al. Ergebnisse der klinischen Prüfung des Glukoneogenesehemmers 2-(3-Methylcinnamylhydrazono)-Propionat (MCHP). [Results of clinical trials with the gluconeogenesis inhibitor 2-(3-methylcinnamylhydrazono)-propionate (MCHP)]. Klin Wochenschr. 1989;67(8):431-7doi: 10.1007/BF01725138.
Paschke, R., Schwedes, U., Kühnle, H., Peter, J., Schmeidl, R., & Usadel, K. H. (1989). Ergebnisse der klinischen Prüfung des Glukoneogenesehemmers 2-(3-Methylcinnamylhydrazono)-Propionat (MCHP). [Results of clinical trials with the gluconeogenesis inhibitor 2-(3-methylcinnamylhydrazono)-propionate (MCHP)]. Klinische Wochenschrift, 67(8), 431-7. https://doi.org/10.1007/BF01725138
Paschke, R, et al. "Ergebnisse der klinischen Prüfung des Glukoneogenesehemmers 2-(3-Methylcinnamylhydrazono)-Propionat (MCHP)." [Results of clinical trials with the gluconeogenesis inhibitor 2-(3-methylcinnamylhydrazono)-propionate (MCHP)]. Klinische Wochenschrift vol. 67,8 (1989): 431-7. doi: https://doi.org/10.1007/BF01725138
Paschke R, Schwedes U, Kühnle H, Peter J, Schmeidl R, Usadel KH. Ergebnisse der klinischen Prüfung des Glukoneogenesehemmers 2-(3-Methylcinnamylhydrazono)-Propionat (MCHP). [Results of clinical trials with the gluconeogenesis inhibitor 2-(3-methylcinnamylhydrazono)-propionate (MCHP)]. Klin Wochenschr. 1989 Apr 17;67(8):431-7. doi: 10.1007/BF01725138. German. PMID: 2498571.
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Klin Wochenschr. 1989 Apr 17;67(8):431-7. doi: 10.1007/BF01725138.

[Results of clinical trials with the gluconeogenesis inhibitor 2-(3-methylcinnamylhydrazono)-propionate (MCHP)].

Klinische Wochenschrift

[Article in German]
R Paschke, U Schwedes, H Kühnle, J Peter, R Schmeidl, K H Usadel

Affiliations

  1. II. Medizinische Klinik, Klinkum Mannheim der Universität Heidelberg, Mannheim.

PMID: 2498571 DOI: 10.1007/BF01725138

Abstract

Many compounds which directly or indirectly inhibit gluconeogenesis have been described. Some of them showed hypoglycemic action in animal experiments. 2-(3-Methylcinnamylhydrazono)-Propionat (MCHP) a derivative of hydrazine demonstrated marked hypoglycemic action in animal experiments. Nontheless the administration of MCHP to type II diabetic patients showed no hypoglycemic action. Clinical or biochemical sideeffects could not be observed.

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