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Nuvole A, Sanna P, Paglietti G, et al. 1,2,3-triazolo[4,5-f]quinolines. II. Preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract (1). Farmaco. 1989;44(6):619-32
Nuvole, A., Sanna, P., Paglietti, G., Juliano, C., Zanetti, S., & Cappuccinelli, P. (1989). 1,2,3-triazolo[4,5-f]quinolines. II. Preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract (1). Farmaco (Societa chimica italiana : 1989), 44(6), 619-32.
Nuvole, A, et al. "1,2,3-triazolo[4,5-f]quinolines. II. Preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract (1)." Farmaco (Societa chimica italiana : 1989) vol. 44,6 (1989): 619-32.
Nuvole A, Sanna P, Paglietti G, Juliano C, Zanetti S, Cappuccinelli P. 1,2,3-triazolo[4,5-f]quinolines. II. Preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract (1). Farmaco. 1989 Jun;44(6):619-32. PMID: 2553038.
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Farmaco. 1989 Jun;44(6):619-32.

1,2,3-triazolo[4,5-f]quinolines. II. Preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract (1).

Farmaco (Societa chimica italiana : 1989)

A Nuvole, P Sanna, G Paglietti, C Juliano, S Zanetti, P Cappuccinelli

Affiliations

  1. Istituto di Chimica Farmaceutica, Università di Sassari, Italy.

PMID: 2553038

Abstract

Some 6-ethyl-1(2)(3)-R-1(2)(3)H-triazolo[4,5-f]quinolin-9-one-8-carboxy lic acids were prepared as novel analogues of oxolinic acid in order to evaluate the effect on antibacterial activity of the isosteric replacement of the dioxolic moiety with the triazole ring substituted in position 1 or 2. In vitro tests showed a good and selective activity against Escherichia coli (MIC 12.5 micrograms/ml) of compound (XVI).

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