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Kitamura K, Senba T, Komatsuzaki A. Bilateral internal auditory canal enlargement without acoustic nerve tumor in von Recklinghausen neurofibromatosis. Neurofibromatosis. 1989;2(1):47-52
Kitamura, K., Senba, T., & Komatsuzaki, A. (1989). Bilateral internal auditory canal enlargement without acoustic nerve tumor in von Recklinghausen neurofibromatosis. Neurofibromatosis, 2(1), 47-52.
Kitamura, K, et al. "Bilateral internal auditory canal enlargement without acoustic nerve tumor in von Recklinghausen neurofibromatosis." Neurofibromatosis vol. 2,1 (1989): 47-52.
Kitamura K, Senba T, Komatsuzaki A. Bilateral internal auditory canal enlargement without acoustic nerve tumor in von Recklinghausen neurofibromatosis. Neurofibromatosis. 1989;2(1):47-52. PMID: 2517023.
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Neurofibromatosis. 1989;2(1):47-52.

Bilateral internal auditory canal enlargement without acoustic nerve tumor in von Recklinghausen neurofibromatosis.

Neurofibromatosis

K Kitamura, T Senba, A Komatsuzaki

Affiliations

  1. Department of Otolaryngology, University of Tokyo, Japan.

PMID: 2517023

Abstract

The common (and definitive) intracranial tumors in patients with one form of neurofibromatosis (NF), bilateral acoustic NF (NF-2), are bilateral acoustic neuromas. In this study, we present 2 cases with what appears to be another form of NF, namely, NF-1, who showed bilateral enlargement of the internal auditory canals. Bilateral caloric responses were remarkably impaired in both cases; a unilateral sensorineural hearing loss was observed in 1. No tumor was demonstrated in the enlarged internal auditory canals in either case. Although the pathophysiology remains uncertain, some patients with NF-1 show abnormal cochleovestibular function in association with bilateral internal auditory canal enlargement without an acoustic tumor.

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