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Rhodes AR, Mihm MC. Origin of cutaneous melanoma in a congenital dysplastic nevus spilus. Arch Dermatol. 1990;126(4):500-5
Rhodes, A. R., & Mihm, M. C. (1990). Origin of cutaneous melanoma in a congenital dysplastic nevus spilus. Archives of dermatology, 126(4), 500-5.
Rhodes, A R, and Mihm, M C. "Origin of cutaneous melanoma in a congenital dysplastic nevus spilus." Archives of dermatology vol. 126,4 (1990): 500-5.
Rhodes AR, Mihm MC. Origin of cutaneous melanoma in a congenital dysplastic nevus spilus. Arch Dermatol. 1990 Apr;126(4):500-5. PMID: 2321995.
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Arch Dermatol. 1990 Apr;126(4):500-5.

Origin of cutaneous melanoma in a congenital dysplastic nevus spilus.

Archives of dermatology

A R Rhodes, M C Mihm

Affiliations

  1. Department of Dermatology, University of Pittsburgh, School of Medicine, PA 15213.

PMID: 2321995

Abstract

Cutaneous melanoma developed in contiguity with a congenital nevus spilus on the leg of a 79-year-old white woman. The unique features of the nevus spilus in this case were its relatively large size (diameter, 8 cm), irregular gross appearance, lifelong stability until the recent appearance of a tumor nodule, and the presence of intraepidermal melanocytic dysplasia appearing as multifocal elements within darkly pigmented speckles distributed throughout a lightly pigmented background of lentigo simplex. Based on this observation, we suggest that the presence of intraepidermal melanocytic dysplasia in nevus spilus may be a predisposing factor for the development of melanoma. The malignant potential of "dysplastic" nevus spilus requires further study.

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