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Metz D, N'Guyen P, Chapoutot L, et al. Embolie pulmonaire massive révélant une thrombopénie induite par héparine de bas poids moléculaire. Succès thérapeutique d'une prostacycline. [Massive pulmonary embolism disclosing thrombocytopenia induced by low molecular weight heparin. Therapeutic success of prostacyclin]. Ann Cardiol Angeiol (Paris). 1991;40(10):619-21
Metz, D., N'Guyen, P., Chapoutot, L., Graciet, J., Taupin, J. M., Grentzinger, A., Elaerts, J., & Bajolet, A. (1991). Embolie pulmonaire massive révélant une thrombopénie induite par héparine de bas poids moléculaire. Succès thérapeutique d'une prostacycline. [Massive pulmonary embolism disclosing thrombocytopenia induced by low molecular weight heparin. Therapeutic success of prostacyclin]. Annales de cardiologie et d'angeiologie, 40(10), 619-21.
Metz, D, et al. "Embolie pulmonaire massive révélant une thrombopénie induite par héparine de bas poids moléculaire. Succès thérapeutique d'une prostacycline." [Massive pulmonary embolism disclosing thrombocytopenia induced by low molecular weight heparin. Therapeutic success of prostacyclin]. Annales de cardiologie et d'angeiologie vol. 40,10 (1991): 619-21.
Metz D, N'Guyen P, Chapoutot L, Graciet J, Taupin JM, Grentzinger A, Elaerts J, Bajolet A. Embolie pulmonaire massive révélant une thrombopénie induite par héparine de bas poids moléculaire. Succès thérapeutique d'une prostacycline. [Massive pulmonary embolism disclosing thrombocytopenia induced by low molecular weight heparin. Therapeutic success of prostacyclin]. Ann Cardiol Angeiol (Paris). 1991 Dec;40(10):619-21. French. PMID: 1723582.
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Ann Cardiol Angeiol (Paris). 1991 Dec;40(10):619-21.

[Massive pulmonary embolism disclosing thrombocytopenia induced by low molecular weight heparin. Therapeutic success of prostacyclin].

Annales de cardiologie et d'angeiologie

[Article in French]
D Metz, P N'Guyen, L Chapoutot, J Graciet, J M Taupin, A Grentzinger, J Elaerts, A Bajolet

Affiliations

  1. Service de Cardiologie, CHR Robert Debré, Reims.

PMID: 1723582

Abstract

The authors report a case of massive pulmonary embolism revealing thrombocytopenia induced by a low molecular weight heparin (LMWH) initially proposed for the treatment of superficial phlebitis. The diagnosis was confirmed by in vitro aggregation tests and a fall in the platelet count when the LMWH was reintroduced. The outcome was clinically, angiographically and hematologically satisfactory in response to in situ treatment with prostaglandin, subsequently replaced by Vitamin K antagonists.

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