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Am J Kidney Dis. 2014 Mar;63(3):500-2. doi: 10.1053/j.ajkd.2013.08.034. Epub 2013 Nov 01.

Management of intraocular hypertension during hemodialysis by intravenous glucose administration.

American journal of kidney diseases : the official journal of the National Kidney Foundation

Turgay Saritas, Antonis Koutsonas, Peter Walter, Jürgen Floege, Thilo Krüger

Affiliations

  1. Department of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany. Electronic address: [email protected].
  2. Department of Ophthalmology, RWTH Aachen University, Aachen, Germany.
  3. Department of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany.

PMID: 24189474 DOI: 10.1053/j.ajkd.2013.08.034

Abstract

A 64-year-old woman with end-stage renal disease and retinopathy secondary to type 2 diabetes mellitus presented with recurrent episodes of left ocular pain and acute loss of visual acuity during hemodialysis. During these episodes, markedly elevated intraocular pressures were measured. Several local and systemic antiglaucoma drugs were administered without improvement of intraocular pressure, resulting in the necessity of a glaucoma drainage device (Ahmed valve). Due to a local infection, it had to be removed, after which intraocular pressure elevations recurred during hemodialysis. Assuming that intraocular changes in osmolality during hemodialysis caused the intraocular pressure increases, intradialytic administration of a 20% glucose solution (100mL/h) was initiated. This completely abrogated the development of both intraocular pain and increases in intraocular pressure.

Copyright © 2014 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Keywords: Hemodialysis; blood glucose; diabetes mellitus; eye; intraocular pressure

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