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Sem Hop. 1977 May 09;53(18):1049-51.

[Initial trial of a new test for the evaluation of hepatocellular function: the TMB test].

La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris

[Article in French]
F Rousselet, A Charbonnier, G Fredj, P Nepveux, G Fluteau, M Cachin

PMID: 196339

Abstract

The oral administration of 400 mg of trimethoxy 1-3-5-benzene or T.M.B. is normally followed by a high urinary excretion of dimethoxy, 1, 3, hydroxy 5 benzene and other metabolites mainly in the form of conjugates. Urinary excretion during the first 3 hours is strongly reduced in liver disease. By a simple blind test we showed that the test is positive in subclinical and laboratory-negative liver failure.

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