Display options
Cite
Rees JD, Stride M, Scott A. Tendons--time to revisit inflammation. Br J Sports Med. 2013;48(21):1553-7doi: 10.1136/bjsports-2012-091957.
Rees, J. D., Stride, M., & Scott, A. (2014). Tendons--time to revisit inflammation. British journal of sports medicine, 48(21), 1553-7. https://doi.org/10.1136/bjsports-2012-091957
Rees, Jonathan D, et al. "Tendons--time to revisit inflammation." British journal of sports medicine vol. 48,21 (2014): 1553-7. doi: https://doi.org/10.1136/bjsports-2012-091957
Rees JD, Stride M, Scott A. Tendons--time to revisit inflammation. Br J Sports Med. 2014 Nov;48(21):1553-7. doi: 10.1136/bjsports-2012-091957. Epub 2013 Mar 09. PMID: 23476034; PMCID: PMC4215290.
Copy Download .nbib Format: NLM
Share it on

Br J Sports Med. 2014 Nov;48(21):1553-7. doi: 10.1136/bjsports-2012-091957. Epub 2013 Mar 09.

Tendons--time to revisit inflammation.

British journal of sports medicine

Jonathan D Rees, Matthew Stride, Alex Scott

Affiliations

  1. Department of Rheumatology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  2. Isokinetic Medical Group, FIFA Medical Centre of Excellence, London, UK.
  3. Department of Physical Therapy, University of British Columbia, Vancouver, Canada.

PMID: 23476034 PMCID: PMC4215290 DOI: 10.1136/bjsports-2012-091957

Abstract

It is currently widely accepted among clinicians that chronic tendinopathy is caused by a degenerative process devoid of inflammation. Current treatment strategies are focused on physical treatments, peritendinous or intratendinous injections of blood or blood products and interruption of painful stimuli. Results have been at best, moderately good and at worst a failure. The evidence for non-infammatory degenerative processes alone as the cause of tendinopathy is surprisingly weak. There is convincing evidence that the inflammatory response is a key component of chronic tendinopathy. Newer anti-inflammatory modalities may provide alternative potential opportunities in treating chronic tendinopathies and should be explored further.

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Keywords: Immune Function; Immunology; Tendons

References

  1. Pain Pract. 2005 Sep;5(3):203-15 - PubMed
  2. Am J Sports Med. 1976 Jul-Aug;4(4):145-50 - PubMed
  3. J Sci Med Sport. 2008 Jun;11(3):235-8 - PubMed
  4. Am J Sports Med. 1998 May-Jun;26(3):360-6 - PubMed
  5. Skeletal Radiol. 2006 Jun;35(6):371-7 - PubMed
  6. J Orthop Res. 2013 Jan;31(1):91-8 - PubMed
  7. Clin J Sport Med. 2005 Jan;15(1):27-33 - PubMed
  8. Knee Surg Sports Traumatol Arthrosc. 2005 May;13(4):338-44 - PubMed
  9. Arthritis Rheum. 2010 Dec;62(12):3799-805 - PubMed
  10. Rheumatology (Oxford). 2006 May;45(5):508-21 - PubMed
  11. J Bone Joint Surg Am. 2010 Nov 3;92(15):2604-13 - PubMed
  12. Reumatismo. 2009 Apr-Jun;61(2):84-9 - PubMed
  13. J Musculoskelet Neuronal Interact. 2011 Jun;11(2):133-40 - PubMed
  14. JAMA. 2010 Jan 13;303(2):144-9 - PubMed
  15. Disabil Rehabil. 2008;30(20-22):1752-8 - PubMed
  16. Knee Surg Sports Traumatol Arthrosc. 1999;7(6):378-81 - PubMed
  17. Br J Sports Med. 2005 Nov;39(11):789-91 - PubMed
  18. J Med Chem. 2012 Aug 23;55(16):7061-79 - PubMed
  19. Osteoarthritis Cartilage. 1999 Jul;7(4):401-2 - PubMed
  20. Med Sci Sports Exerc. 1998 Aug;30(8):1183-90 - PubMed
  21. Clin Orthop Relat Res. 2008 Jul;466(7):1577-82 - PubMed
  22. Anat Embryol (Berl). 1988;179(1):89-96 - PubMed
  23. Rheumatology (Oxford). 2004 Aug;43(8):969-72 - PubMed
  24. Arthritis Rheum. 2006 Mar;54(3):832-42 - PubMed
  25. J Orthop Sci. 2001;6(4):349-57 - PubMed
  26. Osteoarthritis Cartilage. 2011 Jun;19(6):728-36 - PubMed
  27. J Orthop Res. 2010 Feb;28(2):198-203 - PubMed
  28. Am J Sports Med. 2009 Sep;37(9):1855-67 - PubMed
  29. Knee Surg Sports Traumatol Arthrosc. 2012 Aug;20(8):1632-46 - PubMed
  30. Br J Sports Med. 2009 Jun;43(6):409-16 - PubMed
  31. J Bone Joint Surg Am. 2004 Apr;86(4):802-6 - PubMed
  32. Scand J Med Sci Sports. 2009 Jun;19(3):338-44 - PubMed
  33. Arthritis Rheum. 2004 Apr;50(4):1107-16 - PubMed
  34. Clin Orthop Relat Res. 2008 Jul;466(7):1539-54 - PubMed
  35. Am J Sports Med. 2007 Mar;35(3):374-83 - PubMed
  36. South Med J. 1979 Jul;72(7):827-30 - PubMed
  37. Rheumatology (Oxford). 2004 Feb;43(2):131-42 - PubMed
  38. J Orthop Res. 1998 Sep;16(5):618-21 - PubMed
  39. Knee Surg Sports Traumatol Arthrosc. 2003 Sep;11(5):334-8 - PubMed
  40. Scand J Med Sci Sports. 2011 Aug;21(4):562-9 - PubMed
  41. J Sports Sci Med. 2011 Jun 01;10(2):238-53 - PubMed
  42. Br J Sports Med. 2006 Nov;40(11):935-9; discussion 939 - PubMed
  43. J Hand Ther. 2012 Jan-Mar;25(1):5-25; quiz 26 - PubMed
  44. Annu Rev Immunol. 2001;19:163-96 - PubMed
  45. J Orthop Res. 1990 Jul;8(4):541-7 - PubMed
  46. BMJ. 2002 Mar 16;324(7338):626-7 - PubMed
  47. Cochrane Database Syst Rev. 2003;(1):CD004016 - PubMed
  48. Am J Gastroenterol. 2005 Aug;100(8):1685-93 - PubMed
  49. Arthritis Rheum. 2007 Mar;56(3):871-81 - PubMed
  50. BMJ. 2006 Nov 4;333(7575):939 - PubMed
  51. Ann Rheum Dis. 1992 Aug;51(8):1014-8 - PubMed
  52. Rheumatology (Oxford). 2007 Mar;46(3):454-9 - PubMed
  53. Disabil Rehabil. 2008;30(20-22):1697-708 - PubMed
  54. J Orthop Res. 1997 Jan;15(1):33-9 - PubMed
  55. J Clin Immunol. 1999 Nov;19(6):350-64 - PubMed
  56. J Bone Joint Surg Am. 1983 Dec;65(9):1345-7 - PubMed
  57. Clin Orthop Relat Res. 1995 Jul;(316):151-64 - PubMed
  58. Br J Sports Med. 1988 Jun;22(2):64-5 - PubMed
  59. Rheumatology (Oxford). 2012 Jul;51(7):1161-5 - PubMed
  60. Histol Histopathol. 2009 Jul;24(7):839-48 - PubMed
  61. Scand J Med Sci Sports. 2009 Dec;19(6):790-802 - PubMed
  62. Scand J Med Sci Sports. 1997 Apr;7(2):113-8 - PubMed
  63. Ann Rheum Dis. 2005 Jul;64(7):1083-6 - PubMed
  64. Br J Sports Med. 2011 Oct;45(13):1017-22 - PubMed
  65. Matrix Biol. 2002 Mar;21(2):185-95 - PubMed
  66. Nat Med. 2003 Jun;9(6):653-60 - PubMed
  67. Scand J Med Sci Sports. 2001 Aug;11(4):197-206 - PubMed
  68. Sports Med. 1999 Jun;27(6):393-408 - PubMed

Substances

MeSH terms

Publication Types