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Klinke R, Evans EF. Evidence that catecholamines are not the afferent transmitter in the cochlea. Exp Brain Res. 1977;28(3):315-24doi: 10.1007/BF00235713.
Klinke, R., & Evans, E. F. (1977). Evidence that catecholamines are not the afferent transmitter in the cochlea. Experimental brain research, 28(3), 315-24. https://doi.org/10.1007/BF00235713
Klinke, R, and Evans, E F. "Evidence that catecholamines are not the afferent transmitter in the cochlea." Experimental brain research vol. 28,3 (1977): 315-24. doi: https://doi.org/10.1007/BF00235713
Klinke R, Evans EF. Evidence that catecholamines are not the afferent transmitter in the cochlea. Exp Brain Res. 1977 Jun 27;28(3):315-24. doi: 10.1007/BF00235713. PMID: 195827.
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Exp Brain Res. 1977 Jun 27;28(3):315-24. doi: 10.1007/BF00235713.

Evidence that catecholamines are not the afferent transmitter in the cochlea.

Experimental brain research

R Klinke, E F Evans

PMID: 195827 DOI: 10.1007/BF00235713

Abstract

Beta-receptor blocking agents (practolol, propranolol) and alpha-receptor blocking agents (phenoxybenzamine, phentolamine), when applied intracochlearly do not eliminate the afferetn discharges or compound action potential of the cochlear nerve. Under the assumption that the drugs used reach the synaptic site, it is therefore concluded that these drugs do not interfere with afferent synaptic transmission. Phentolamine,, however, has a toxic effect upon the cochlea independent from the synaptic process. Local application of catecholamines does not increase spontaneous activity of single fibres of the cochlear nerve. These findings show that catecholamines are not likely to be the afferent transmitter.

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References

  1. J Pharmacol Exp Ther. 1967 Apr;156(1):39-47 - PubMed
  2. Can J Physiol Pharmacol. 1976 Feb;54(1):42-8 - PubMed
  3. Jpn J Physiol. 1967 Oct 15;17(5):572-88 - PubMed
  4. Ann N Y Acad Sci. 1967 Feb 10;139(3):952-67 - PubMed
  5. Science. 1970 Jan 2;167(3914):76-9 - PubMed
  6. Biophys J. 1962 Jan;2:23-34 - PubMed
  7. J Gen Physiol. 1971 Nov;58(5):580-98 - PubMed
  8. Brain Res. 1974 May 31;72(1):79-97 - PubMed
  9. Brain Res. 1976 Jun 18;109(3):575-85 - PubMed
  10. Science. 1966 Mar 25;151(3717):1544-5 - PubMed
  11. Nature. 1974 May 10;249(453):142-4 - PubMed
  12. Z Zellforsch Mikrosk Anat. 1972;127(3):347-55 - PubMed
  13. J Physiol. 1974 Oct;242(2):129P - PubMed
  14. Brain Res. 1974 May 31;72(1):99-114 - PubMed
  15. Cell Tissue Res. 1975 Nov 7;163(2):239-47 - PubMed
  16. J Physiol. 1976 May;257(1):45-62 - PubMed
  17. J Histochem Cytochem. 1976 Feb;24(2):468-70 - PubMed
  18. Jpn J Physiol. 1972 Dec;22(6):617-35 - PubMed
  19. Acta Otolaryngol. 1975 May-Jun;79(5-6):339-51 - PubMed
  20. Physiol Rev. 1974 Apr;54(2):316-57 - PubMed
  21. J Physiol. 1974 Apr;238(1):65P-67P - PubMed
  22. Brain Res. 1971 Feb 5;25(3):523-34 - PubMed
  23. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;259(2):191-2 - PubMed
  24. J Acoust Soc Am. 1974 Mar;55(3):606-19 - PubMed
  25. J Gen Physiol. 1964 May;47:965-74 - PubMed
  26. J Neurophysiol. 1954 Mar;17(2):97-122 - PubMed
  27. J Neurophysiol. 1952 Nov;15(6):497-512 - PubMed
  28. Brain Res. 1973 Dec 21;64:55-63 - PubMed
  29. Arch Klin Exp Ohren Nasen Kehlkopfheilkd. 1967;189(4):346-59 - PubMed
  30. Laryngoscope. 1975 Jul;85(7):1241-58 - PubMed
  31. Acta Otolaryngol. 1966 May;61(5):423-34 - PubMed
  32. Acta Otolaryngol. 1974 Mar;77(3):185-97 - PubMed
  33. Arch Otorhinolaryngol. 1974;208(4):283-93 - PubMed
  34. Exp Brain Res. 1977 Jun 27;28(3-4):311-4 - PubMed
  35. J Physiol. 1972 Oct;226(1):263-87 - PubMed

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