Display options
Share it on

Indian J Otolaryngol Head Neck Surg. 2005 Jan;57(1):21-3. doi: 10.1007/BF02907620.

Intratympanic dexamethasone application in Meniere's disease-Is it superior to conventional therapy?.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

Gilbert Paragache, Naresh K Panda, Meena Ragunathan, Sridhara

Affiliations

  1. Department of Otolaryngology and Head and Neck Surgery, Post Graduate Institute for Medical Education and Research, Chandigarh, India.

PMID: 23120117 PMCID: PMC3451534 DOI: 10.1007/BF02907620

Abstract

OBJECTIVE: To compare the efficacy of conventional medical treatment versus transtympanic dexamethasone application into middle ear as treatment modality in Meniere's disease.

STUDY DESIGN: Prospective randomized study.

SETTING: Tertiary referral centre.

METHOD: Forty patients of Meniere's disease were treated, 20 by conventional method and 20 by transtympanic dexamethasone applications.

INTERVENTION: Theraputic.

RESULTS: Vertigo control of 85% achieved in study group when compared to 80% in control group, 15% of patients had hearing improvement in study group while 10% had hearing improvement in control group. Aural fullness and tinnitus control were identical in both groups.

CONCLUSIONS: Both modalities of therapy were found to have almost equal efficacy, with Intra tympanic steroid (ITS) therapy having an edge over conventional therapy in cases with severe attacks and shorter duration of symptoms.

Keywords: Dexamethasone; Intra tympanic steroid; Meniere's disease

References

  1. Ear Nose Throat J. 1999 Aug;78(8):595-8, 600 - PubMed
  2. Otolaryngol Head Neck Surg. 1993 Oct;109(4):680-9 - PubMed
  3. Acta Otolaryngol Suppl. 1996;522:79-85 - PubMed
  4. Ann Otol Rhinol Laryngol. 2000 Dec;109(12 Pt 1):1093-8 - PubMed
  5. Acta Otolaryngol Suppl. 1991;479:44-7 - PubMed
  6. Otolaryngol Clin North Am. 1996 Apr;29(2):353-8 - PubMed
  7. Laryngoscope. 1998 Nov;108(11 Pt 1):1682-5 - PubMed
  8. ORL J Otorhinolaryngol Relat Spec. 1994;56(1):11-8 - PubMed
  9. Ann Otol Rhinol Laryngol. 1979 Sep-Oct;88(5 Pt 1):585-9 - PubMed
  10. Arch Otolaryngol. 1985 Sep;111(9):609-12 - PubMed
  11. Laryngoscope. 2001 Dec;111(12):2100-4 - PubMed
  12. Acta Otolaryngol Suppl. 1988;455:77-81 - PubMed
  13. Otolaryngol Head Neck Surg. 2001 Nov;125(5):537-43 - PubMed
  14. Acta Otolaryngol Suppl. 1991;481:617-23 - PubMed

Publication Types