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HighWire Free PMC Article

Ann Rheum Dis. 1990 Dec;49(12):999-1000. doi: 10.1136/ard.49.12.999.

Sparing effect of hemiplegia on scleroderma.

Annals of the rheumatic diseases

S Sethi, W Sequeira

Affiliations

  1. Department of Medicine, Cook County Hospital, Chicago, Illinois.

PMID: 2270974 PMCID: PMC1004296 DOI: 10.1136/ard.49.12.999
Free PMC Article

Abstract

The paretic limb is spared in patients who develop rheumatic diseases after a hemiplegic stroke. This has been described previously in rheumatoid arthritis, gout, and osteoarthritis. A similar presentation in a case of scleroderma is described in this report. Scleroderma skin changes are absent in the completely paretic limb and were markedly reduced in the weak left leg. Inflammation may be modified either by neuropeptides or by an anatomical neurological lesion and this may explain the phenomenon.

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