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Solsona E, Iborra I, Ricos JV, et al. Comportamiento biológico del carcinoma in situ vesical no tratado. [Biological behavior of untreated bladder carcinoma in situ]. Arch Esp Urol. 1990;43(6):643-5
Solsona, E., Iborra, I., Ricos, J. V., Monrós, J. L., Dumont, R., Mazcuñán, F., Casanova, J., & Calabuig, C. (1990). Comportamiento biológico del carcinoma in situ vesical no tratado. [Biological behavior of untreated bladder carcinoma in situ]. Archivos espanoles de urologia, 43(6), 643-5.
Solsona, E, et al. "Comportamiento biológico del carcinoma in situ vesical no tratado." [Biological behavior of untreated bladder carcinoma in situ]. Archivos espanoles de urologia vol. 43,6 (1990): 643-5.
Solsona E, Iborra I, Ricos JV, Monrós JL, Dumont R, Mazcuñán F, Casanova J, Calabuig C. Comportamiento biológico del carcinoma in situ vesical no tratado. [Biological behavior of untreated bladder carcinoma in situ]. Arch Esp Urol. 1990 Jul-Aug;43(6):643-5. Spanish. PMID: 2092618.
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Arch Esp Urol. 1990 Jul-Aug;43(6):643-5.

[Biological behavior of untreated bladder carcinoma in situ].

Archivos espanoles de urologia

[Article in Spanish]
E Solsona, I Iborra, J V Ricos, J L Monrós, R Dumont, F Mazcuñán, J Casanova, C Calabuig

Affiliations

  1. Servicio de Anatomía Patológica, Instituto Valenciano de Oncología (IVO), Valencia, España.

PMID: 2092618

Abstract

The biological behaviour of initially untreated carcinoma in situ of the bladder was studied in 20 patients. A 35.4-month follow-up revealed a heterogeneous behaviour of this disease entity. Diffuse tumors were clearly distinct from focal tumors. The evolution of the former appeared to be more aggressive: no spontaneous remission was observed, 58.3% remained as such while 41.6% progressed to muscle layer infiltration. Focal tumors evolved more favourably: only 1 (12.5%) developed into diffuse carcinoma in situ, 2 (25%) continued to be positive for cytology, while 4 (50%) remitted spontaneously. We therefore consider that both patient groups must be treated upon diagnosis. Intravesical treatment, which achieves a high rate of complete response, is advocated.

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