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S. Karger AG, Basel, Switzerland

Ophthalmic Res. 1990;22(5):271-9. doi: 10.1159/000267035.

Development of light dissemination in the rat lens after in vivo exposure to radiation in the 300-nm wavelength region.

Ophthalmic research

P G Söderberg

Affiliations

  1. Department of Ophthalmology, Karolinska Institute, Stockholm, Sweden.

PMID: 2090981 DOI: 10.1159/000267035

Abstract

The course of development of light dissemination was investigated for rat lenses exposed in vivo to 30 kJ/m2 ultraviolet radiation (UVR) in the 300-nm wavelength region. After an initial latency phase the light dissemination increases rapidly. At 72 h after the exposure to UVR, light dissemination almost reaches a maximum. An exponential model is proposed for the analysis of this pattern. Light dissemination also increases in lenses contralateral to exposed. This indicates that there may be a systemic response after exposure to UVR which can lead to cataract formation.

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