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Ulinski T, Sellier-Leclerc AL, Tudorache E, et al. Acute tubulointerstitial nephritis. Pediatr Nephrol. 2011;27(7):1051-7doi: 10.1007/s00467-011-1915-9.
Ulinski, T., Sellier-Leclerc, A. L., Tudorache, E., Bensman, A., & Aoun, B. (2012). Acute tubulointerstitial nephritis. Pediatric nephrology (Berlin, Germany), 27(7), 1051-7. https://doi.org/10.1007/s00467-011-1915-9
Ulinski, Tim, et al. "Acute tubulointerstitial nephritis." Pediatric nephrology (Berlin, Germany) vol. 27,7 (2012): 1051-7. doi: https://doi.org/10.1007/s00467-011-1915-9
Ulinski T, Sellier-Leclerc AL, Tudorache E, Bensman A, Aoun B. Acute tubulointerstitial nephritis. Pediatr Nephrol. 2012 Jul;27(7):1051-7. doi: 10.1007/s00467-011-1915-9. Epub 2011 Jun 03. PMID: 21638156.
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Pediatr Nephrol. 2012 Jul;27(7):1051-7. doi: 10.1007/s00467-011-1915-9. Epub 2011 Jun 03.

Acute tubulointerstitial nephritis.

Pediatric nephrology (Berlin, Germany)

Tim Ulinski, Anne-Laure Sellier-Leclerc, Elena Tudorache, Albert Bensman, Bilal Aoun

Affiliations

  1. Department of Pediatric Nephrology, Armand Trousseau Hospital (APHP), University Pierre & Marie Curie, Paris 6, 26, Avenue du Docteur Arnold Netter, 75012, Paris, France. [email protected]

PMID: 21638156 DOI: 10.1007/s00467-011-1915-9

Abstract

Acute tubulointerstitial nephritis (TIN) is a frequent cause of acute renal failure, characterised by the presence of inflammatory cell infiltrate in the interstitium of the kidney. Immuno-allergic reaction to certain medications, mainly non-steroidal anti-inflammatory drugs and antibiotics are by far the most important etiology for TIN today, but other situations such as infections, toxins, and vasculitis are known to induce TIN. Incidence of TIN is increasing, probably due to prescription habits and NSAID overuse, representing 3-7% of acute kidney injury in biopsies in children. Avoidance of the causal substance and rapid steroid therapy are hallmarks for patient care, but spontaneous initial recovery is very frequent and the general prognosis seems satisfactory. However, development of chronic TIN, without response to steroid or other immunosuppressive treatment, is possible. As the largest part of TIN is secondary to certain drugs, clear indications in particular for NSAID or antibiotics should be respected to reduce the number of TIN cases.

References

  1. Kidney Int. 1989 May;35(5):1257-70 - PubMed
  2. Pediatr Nephrol. 1999 Jun;13(5):426-32 - PubMed
  3. Nephrol Dial Transplant. 2004 Nov;19(11):2778-83 - PubMed
  4. Nephrol Dial Transplant. 2003 Nov;18(11):2300-7 - PubMed
  5. Contrib Nephrol. 1987;55:159-75 - PubMed
  6. Kidney Int. 2010 May;77(9):820-9 - PubMed
  7. Am J Kidney Dis. 1989 Dec;14(6):466-71 - PubMed
  8. Am J Nephrol. 1990;10(3):222-30 - PubMed
  9. Chest. 1998 Oct;114(4):1220-3 - PubMed
  10. Child Nephrol Urol. 1990;10(4):189-95 - PubMed
  11. Clin Nephrol. 2000 Sep;54(3):179-90 - PubMed
  12. Kidney Int. 2010 Jun;77(11):956-61 - PubMed
  13. Hum Immunol. 2008 Dec;69(12):840-4 - PubMed
  14. Invest Ophthalmol Vis Sci. 2003 Feb;44(2):653-7 - PubMed
  15. Pediatr Nephrol. 2010 Jul;25(7):1349-53 - PubMed
  16. Clin Nephrol. 2000 Sep;54(3):191-7 - PubMed
  17. Pediatr Nephrol. 1992 Nov;6(6):547-9 - PubMed
  18. J Rheumatol. 2006 Dec;33(12):2551 - PubMed
  19. Am J Physiol Renal Physiol. 2001 Apr;280(4):F562-73 - PubMed
  20. Immunology. 1995 Oct;86(2):190-8 - PubMed
  21. Inflamm Bowel Dis. 2011 Apr;17(4):1034-45 - PubMed
  22. Am J Pathol. 2007 Feb;170(2):457-68 - PubMed
  23. Acta Ophthalmol. 2009 Sep;87(6):676-9 - PubMed
  24. Pediatrics. 1981 Jun;67(6):862-70 - PubMed
  25. Contrib Nephrol. 2011;169:262-269 - PubMed
  26. Am J Med. 1984 Jun;76(6):1006-12 - PubMed
  27. Nat Rev Nephrol. 2010 Aug;6(8):461-70 - PubMed
  28. N Engl J Med. 1989 Sep 7;321(10):625-30 - PubMed
  29. Acta Pathol Jpn. 1989 Sep;39(9):551-7 - PubMed
  30. Int Ophthalmol Clin. 2008 Summer;48(3):51-9 - PubMed
  31. Ophthalmology. 2007 May;114(5):995-9 - PubMed
  32. Curr Opin Crit Care. 2008 Dec;14(6):647-53 - PubMed
  33. Kidney Int. 2007 Oct;72(8):918-25 - PubMed
  34. West Indian Med J. 2008 Jun;57(3):246-52 - PubMed
  35. Aust N Z J Med. 1990 Apr;20(2):170-2 - PubMed
  36. Clin J Am Soc Nephrol. 2007 Mar;2(2):222-30 - PubMed
  37. Pediatr Nephrol. 2008 Nov;23(11):2091-3 - PubMed
  38. Virchows Arch. 1996 Apr;428(1):5-12 - PubMed
  39. Contrib Nephrol. 2007;153:87-104 - PubMed
  40. Kidney Int. 2008 Apr;73(8):940-6 - PubMed
  41. Bol Med Hosp Infant Mex. 1981 Mar-Apr;38(2):259-67 - PubMed
  42. J Nephrol. 2009 Nov-Dec;22(6):739-46 - PubMed
  43. Ann Rheum Dis. 2007 Apr;66(4):548-50 - PubMed
  44. Kidney Int. 2001 Aug;60(2):804-17 - PubMed
  45. Tohoku J Exp Med. 1999 Oct;189(2):155-61 - PubMed
  46. J Am Soc Nephrol. 1996 Jun;7(6):906-13 - PubMed
  47. Nephrol Dial Transplant. 2004 Jan;19(1):8-11 - PubMed
  48. J Pediatr. 2007 Aug;151(2):215-7 - PubMed
  49. J Nephrol. 2000 Sep-Oct;13(5):373-6 - PubMed
  50. Pediatr Nephrol. 2011 Feb;26(2):291-9 - PubMed
  51. Pediatr Nephrol. 2007 Jun;22(6):887-8 - PubMed
  52. J Pediatr Gastroenterol Nutr. 2008 Mar;46(3):338-41 - PubMed
  53. Clin Nephrol. 2010 Mar;73(3):247-9 - PubMed
  54. Clin Nephrol. 2005 Aug;64(2):155-8 - PubMed
  55. Am J Kidney Dis. 1999 May;33(5):e3 - PubMed
  56. J Assoc Physicians India. 2004 Aug;52:632-40 - PubMed
  57. Pediatr Nephrol. 2005 Dec;20(12):1805-8 - PubMed
  58. Semin Arthritis Rheum. 2002 Oct;32(2):125-9 - PubMed
  59. Surv Ophthalmol. 2001 Nov-Dec;46(3):195-208 - PubMed
  60. Pediatr Nephrol. 2005 Jun;20(6):814-7 - PubMed
  61. Kidney Int. 2006 Dec;70(12):2074-84 - PubMed
  62. Clin Exp Nephrol. 2005 Mar;9(1):79-84 - PubMed
  63. Clin J Am Soc Nephrol. 2011 Jan;6(1):93-100 - PubMed
  64. Am J Ophthalmol. 2000 Jun;129(6):764-8 - PubMed
  65. Clin J Am Soc Nephrol. 2006 Jul;1(4):718-22 - PubMed
  66. Am J Nephrol. 1989;9(6):499-503 - PubMed

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