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J Oral Microbiol. 2010 Dec 21;2. doi: 10.3402/jom.v2i0.5818.

Diabetes, periodontitis, and the subgingival microbiota.

Journal of oral microbiology

Edward J Ohlrich, Mary P Cullinan, Jonathan W Leichter

Affiliations

  1. Department of Oral Sciences, School of Dentistry, University of Otago, Dunedin, New Zealand.

PMID: 21523215 PMCID: PMC3084563 DOI: 10.3402/jom.v2i0.5818

Abstract

Both type 1 and type 2 diabetes have been associated with increased severity of periodontal disease for many years. More recently, the impact of periodontal disease on glycaemic control has been investigated. The role of the oral microbiota in this two-way relationship is at this stage unknown. Further studies, of a longitudinal nature and investigating a wider array of bacterial species, are required in order to conclusively determine if there is a difference in the oral microbiota of diabetics and non-diabetics and whether this difference accounts, on the one hand, for the increased severity of periodontal disease and on the other for the poorer glycaemic control seen in diabetics.

Keywords: diabetes; metabolic control; periodontitis; subgingival microbiota

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