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Miller M, Kwiterovich PO. Isolated low HDL-cholesterol as an important risk factor for coronary heart disease. Eur Heart J. 1990;11:9-14doi: 10.1093/eurheartj/11.suppl_h.9.
Miller, M., & Kwiterovich, P. O. (1990). Isolated low HDL-cholesterol as an important risk factor for coronary heart disease. European heart journal, 119-14. https://doi.org/10.1093/eurheartj/11.suppl_h.9
Miller, M, and Kwiterovich, P O. "Isolated low HDL-cholesterol as an important risk factor for coronary heart disease." European heart journal vol. 11 (1990): 9-14. doi: https://doi.org/10.1093/eurheartj/11.suppl_h.9
Miller M, Kwiterovich PO. Isolated low HDL-cholesterol as an important risk factor for coronary heart disease. Eur Heart J. 1990 Dec;11:9-14. doi: 10.1093/eurheartj/11.suppl_h.9. PMID: 2073916.
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Eur Heart J. 1990 Dec;11:9-14. doi: 10.1093/eurheartj/11.suppl_h.9.

Isolated low HDL-cholesterol as an important risk factor for coronary heart disease.

European heart journal

M Miller, P O Kwiterovich

Affiliations

  1. Lipid Research-Atherosclerosis Unit, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

PMID: 2073916 DOI: 10.1093/eurheartj/11.suppl_h.9

Abstract

Decreased levels of high density lipoprotein (HDL)-cholesterol are found in patients with hypertriglyceridaemia and in patients who have inherited disorders associated with premature coronary heart disease. Hereditary conditions associated with low levels of HDL-cholesterol and normal total cholesterol levels include familial hypoalphalipoproteinaemia, Tangier disease, fish eye disease, and lecithin: cholesterol acyltransferase deficiency. Secondary causes of low HDL-cholesterol levels include any condition that affects liver metabolism. A recent study of patients with coronary artery disease (CAD) who had normal levels of low density lipoprotein cholesterol and total cholesterol revealed that two-thirds of the men and four-fifths of the women had low HDL-cholesterol levels, suggesting that low HDL-cholesterol may be more prevalent than previously suspected. The high incidence of isolated hypoalphalipoproteinaemia in this group indicates that HDL-cholesterol measurements should be performed on all patients with CAD, regardless of their total cholesterol levels.

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PMID: 34447653

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