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Riv Eur Sci Med Farmacol. 1990 Jun;12(3):165-8.

[Oral contraceptive and hepatic effects].

Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques

[Article in Italian]
G Tarantino, L Morelli, C Califano

Affiliations

  1. Istituto di Medicina Interna e Malattie Dismetaboliche, II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli.

PMID: 2101166

Abstract

The general use of synthetic estrogens like DC pointed out that near many skilled collateral effects, some others that are showing with a decrease of bile excretion (cholestasis), reversible with their administration interruption; with hepatic cells adenoma that are potentially premalignant and can transform into hepatocellular carcinoma; with vascular complications such as (most frequently in carcinomatousis) "hepatic peliosis" and "thrombosis" of suprahepatic veins (Budd-Chiari's syndrome). There is no overall increase in the incidence of gallbladder disease (cholelithiasis and cholecystitis).

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