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Scand J Haematol. 1978 Nov;21(5):418-20. doi: 10.1111/j.1600-0609.1978.tb00388.x.

Non-randomness in complex translocations of chronic myeloid leukaemia.

Scandinavian journal of haematology

R Berger, A Bernheim

PMID: 282661 DOI: 10.1111/j.1600-0609.1978.tb00388.x

Abstract

A new case of chronic myeloid leukaemia with a complex translocation involving chromosomes No. 1, 9 and 22 is reported. The striking similarity of this case with another previously reported case and the involvement of band 9q34 in chromosome rearrangements in CML patients indicates clearly a non-randomness of chromosome abnormalities in this blood disease, even when the translocation is different from the usual t(9;22) one. The usefulness of R-banding techniques is emphasized in these cases.

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