Display options
Share it on
Full text links
Wolters Kluwer

ASAIO Trans. 1990 Apr-Jun;36(2):119-21. doi: 10.1097/00002480-199004000-00013.

An intraperitoneal insulin regimen for diabetics on continuous cyclic peritoneal dialysis.

ASAIO transactions

N S Aujla, B Piraino, M I Sorkin

Affiliations

  1. Department of Medicine, University of Pittsburgh School of Medicine, PA.

PMID: 2187506 DOI: 10.1097/00002480-199004000-00013

Abstract

Intraperitoneal insulin requirements were evaluated in six diabetic patients who were switched from continuous ambulatory peritoneal dialysis to continuous cyclic peritoneal dialysis. The mean total daily intraperitoneal insulin dose on continuous cyclic peritoneal dialysis was 85% of the mean dose on continuous ambulatory peritoneal dialysis (66 +/- 33 vs. 78 +/- 47 units/day, respectively, not significant), with comparable glycemic control. Twenty-five to 58% (mean value, 41%) of the total daily intraperitoneal insulin was administered in the diurnal exchange of the patients on continuous cyclic peritoneal dialysis. The ratio of the total intraperitoneal insulin dose on continuous cyclic peritoneal dialysis to the subcutaneous insulin dose predialysis was between 1.2 and 2.4 (mean value, 1.9). As guidelines for converting intraperitoneal insulin doses for patients switched from continuous ambulatory peritoneal dialysis to continuous cyclic peritoneal dialysis, we recommend starting continuous cyclic peritoneal dialysis with a total daily insulin dose 15% less than the continuous ambulatory peritoneal dialysis dose and giving approximately 40% of the total daily insulin dose in the diurnal exchange.

Similar articles

Show all 14 similar articles

Substances

MeSH terms

Publication Types

LinkOut - more resources