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Wiley

J Am Geriatr Soc. 1975 Jan;23(1):22-30. doi: 10.1111/j.1532-5415.1975.tb00376.x.

Collagenase in the treatment of dermal and decubitus ulcers.

Journal of the American Geriatrics Society

D B Rao, P G Sane, E L Georgiev

PMID: 162802 DOI: 10.1111/j.1532-5415.1975.tb00376.x

Abstract

The current management of decubitus ulcers, factors in wound healing and the role of enzymes in treatment are discussed. The therapeutic benefits of collagenase (Santyl) ointment in 21 patients are described, supplemented by serial color photographs. Statistical evidence is provided for the conclusion that collagenase ointment is an excellent adjunct to therapy.

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