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Acta Pol Pharm. 2009 Jul-Aug;66(4):429-31.

Tablets coated with the novel starch hydrolysate emulsion.

Acta poloniae pharmaceutica

Wiktor Czarnecki, Piotr Belniak

Affiliations

  1. Chair and Department of Applied Pharmacy, Faculty of Pharmacy, Medical University, 1 Chod?ki St., 20-093 Lublin, Poland.

PMID: 19702176

Abstract

The purpose of this study was to investigate coating process of tablets with the novel starch hydrolysate emulsion. The process was performed manually in a coating pan rotating 35 rpm, with a stream of dry air (40 - 45 degrees C). The coated tablets were of fairly good quality. A total tablet surface was calculated for evaluation of quantity of starch hydrolysate emulsion for one step of coating process, which was repeated 10 times. The average weight of coated tablet was increased by 7.323% (w/w) with disposition of solid ingredients of coating emulsion - 75.69% (w/w) on a tablet's surface and 24.31% (w/w) on an interior surface of pan-coating. The average single coating thickness amounts to 21 microm. On the basis of presented results it can be concluded that the starch hydrolysate emulsion may be considered as an alternative coating formulation to be used for pharmaceutical purposes.

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