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Postgrad Med. 2003 Dec;114(6):4-10. doi: 10.3810/pgm.12.2003.suppl33.198.

The role of sympathetic activation in cardiovascular disease.

Postgraduate medicine

Jerome D Cohen, Brent M Egan

Affiliations

  1. St Louis University Health Sciences Center, 3525 Caroline St, St Louis, MO 63104, USA. [email protected]

PMID: 19667664 DOI: 10.3810/pgm.12.2003.suppl33.198

Abstract

Activation of the sympathetic nervous system plays an important role in the development and maintenance of essential hypertension and the subsequent development of cardiac hypertrophy, heart failure, and sudden cardiac death. Current research suggests that pharmacologic treatment of hypertension should be aimed not only at lowering blood pressure, but also at inhibiting sympathetic drive.

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