Postgrad Med. 2003 Dec;114(6):4-10. doi: 10.3810/pgm.12.2003.suppl33.198.
Postgraduate medicine
Jerome D Cohen, Brent M Egan
PMID: 19667664 DOI: 10.3810/pgm.12.2003.suppl33.198
Activation of the sympathetic nervous system plays an important role in the development and maintenance of essential hypertension and the subsequent development of cardiac hypertrophy, heart failure, and sudden cardiac death. Current research suggests that pharmacologic treatment of hypertension should be aimed not only at lowering blood pressure, but also at inhibiting sympathetic drive.