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Funato M, Fukao T, Sasai H, et al. Translocation (1;10)(p34;p15) in infant acute myeloid leukemia with extramedullary infiltration in multiple sites. Cancer Genet Cytogenet. 2009;192(2):86-9doi: 10.1016/j.cancergencyto.2009.04.010.
Funato, M., Fukao, T., Sasai, H., Hori, T., Terazawa, D., Ozeki, M., Orii, K., Teramoto, T., Kaneko, H., & Kondo, N. (2009). Translocation (1;10)(p34;p15) in infant acute myeloid leukemia with extramedullary infiltration in multiple sites. Cancer genetics and cytogenetics, 192(2), 86-9. https://doi.org/10.1016/j.cancergencyto.2009.04.010
Funato, Michinori, et al. "Translocation (1;10)(p34;p15) in infant acute myeloid leukemia with extramedullary infiltration in multiple sites." Cancer genetics and cytogenetics vol. 192,2 (2009): 86-9. doi: https://doi.org/10.1016/j.cancergencyto.2009.04.010
Funato M, Fukao T, Sasai H, Hori T, Terazawa D, Ozeki M, Orii K, Teramoto T, Kaneko H, Kondo N. Translocation (1;10)(p34;p15) in infant acute myeloid leukemia with extramedullary infiltration in multiple sites. Cancer Genet Cytogenet. 2009 Jul 15;192(2):86-9. doi: 10.1016/j.cancergencyto.2009.04.010. PMID: 19596261.
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Cancer Genet Cytogenet. 2009 Jul 15;192(2):86-9. doi: 10.1016/j.cancergencyto.2009.04.010.

Translocation (1;10)(p34;p15) in infant acute myeloid leukemia with extramedullary infiltration in multiple sites.

Cancer genetics and cytogenetics

Michinori Funato, Toshiyuki Fukao, Hideo Sasai, Tomohiro Hori, Daisuke Terazawa, Michio Ozeki, Kenji Orii, Takahide Teramoto, Hideo Kaneko, Naomi Kondo

Affiliations

  1. Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu, Japan.

PMID: 19596261 DOI: 10.1016/j.cancergencyto.2009.04.010

Abstract

Primary acute myeloid leukemia (AML) with extramedullary infiltration (EMI) in multiple sites is rare. Herein, we describe a case of infant AML with EMI in multiple sites. She had dyspnea and hypofibrinogenemia at diagnosis, and systemic computed tomography revealed EMI in the orbit, gingiva, bronchial pathway, and urinary tract. Bone marrow examination confirmed the diagnosis of AML with t(1;10)(p34;p15). No case of AML with t(1;10)(p34;p15) has been reported in the literature. At the present time, she remains free of disease 12 months after bone marrow transplantation (BMT) in the second complete remission.

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