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Trans R Soc Trop Med Hyg. 1991 Jan-Feb;85(1):8-11. doi: 10.1016/0035-9203(91)90137-n.

Recent developments in the nutritional management of diarrhoea. 2. Chronic diarrhoea and malnutrition in The Gambia: studies on intestinal permeability.

Transactions of the Royal Society of Tropical Medicine and Hygiene

P G Lunn, C A Northrop-Clewes, R M Downes

Affiliations

  1. Medical Research Council, Dunn Nutrition Unit, Cambridge, UK.

PMID: 1906207 DOI: 10.1016/0035-9203(91)90137-n

Abstract

Chronic diarrhoea and malnutrition in Gambian children is associated with persisting damage to the mucosa of the small intestine. Intestinal permeability tests suggest that mucosal status gradually deteriorates with age throughout the first year of life in tandem with increasingly severe growth faltering. The ability of the dual sugar permeability test to assess intestinal mucosal status frequently in a non-invasive way makes the technique a valuable tool for future studies into the aetiology of this syndrome.

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