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Acott TS, Kelley MJ. Extracellular matrix in the trabecular meshwork. Exp Eye Res. 2008;86(4):543-61doi: 10.1016/j.exer.2008.01.013.
Acott, T. S., & Kelley, M. J. (2008). Extracellular matrix in the trabecular meshwork. Experimental eye research, 86(4), 543-61. https://doi.org/10.1016/j.exer.2008.01.013
Acott, Ted S, and Kelley, Mary J. "Extracellular matrix in the trabecular meshwork." Experimental eye research vol. 86,4 (2008): 543-61. doi: https://doi.org/10.1016/j.exer.2008.01.013
Acott TS, Kelley MJ. Extracellular matrix in the trabecular meshwork. Exp Eye Res. 2008 Apr;86(4):543-61. doi: 10.1016/j.exer.2008.01.013. Epub 2008 Jan 25. PMID: 18313051; PMCID: PMC2376254.
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Exp Eye Res. 2008 Apr;86(4):543-61. doi: 10.1016/j.exer.2008.01.013. Epub 2008 Jan 25.

Extracellular matrix in the trabecular meshwork.

Experimental eye research

Ted S Acott, Mary J Kelley

Affiliations

  1. Casey Eye Institute, Oregon Health & Science University, 3375 SW Terwilliger, Portland, OR 97239-4197, USA. [email protected]

PMID: 18313051 PMCID: PMC2376254 DOI: 10.1016/j.exer.2008.01.013

Abstract

The extracellular matrix (ECM) of the trabecular meshwork (TM) is thought to be important in regulating intraocular pressure (IOP) in both normal and glaucomatous eyes. IOP is regulated primarily by a fluid resistance to aqueous humor outflow. However, neither the exact site nor the identity of the normal resistance to aqueous humor outflow has been established. Whether the site and nature of the increased outflow resistance, which is associated with open-angle glaucoma, is the same or different from the normal resistance is also unclear. The ECMs of the TM beams, juxtacanalicular region (JCT) and Schlemm's canal (SC) inner wall are comprised of fibrillar and non-fibrillar collagens, elastin-containing microfibrils, matricellular and structural organizing proteins, glycosaminoglycans (GAGs) and proteoglycans. Both basement membranes and stromal ECM are present in the TM beams and JCT region. Cell adhesion proteins, cell surface ECM receptors and associated binding proteins are also present in the beams, JCT and SC inner wall region. The outflow pathway ECM is relatively dynamic, undergoing constant turnover and remodeling. Regulated changes in enzymes responsible for ECM degradation and biosynthetic replacement are observed. IOP homeostasis, triggered by pressure changes or mechanical stretching of the TM, appears to involve ECM turnover. Several cytokines, growth factors and drugs, which affect the outflow resistance, change ECM component expression, mRNA alternative splicing, cellular cytoskeletal organization or all of these. Changes in ECM associated with open-angle glaucoma have been identified.

References

  1. Invest Ophthalmol Vis Sci. 2006 Jan;47(1):213-21 - PubMed
  2. J Biol Chem. 2003 Apr 25;278(17):15326-32 - PubMed
  3. Acta Soc Med Ups. 1954 Mar 31;59(3-4):260-76 - PubMed
  4. Int J Biochem Cell Biol. 2004 Jun;36(6):986-90 - PubMed
  5. Invest Ophthalmol Vis Sci. 1988 Jan;29(1):90-100 - PubMed
  6. Cell Struct Funct. 2001 Jun;26(3):179-87 - PubMed
  7. Invest Ophthalmol Vis Sci. 1985 Oct;26(10):1320-9 - PubMed
  8. Ophthalmic Res. 1998;30(5):314-20 - PubMed
  9. Exp Eye Res. 1981 Mar;32(3):265-77 - PubMed
  10. J Biol Chem. 1991 Aug 5;266(22):14763-70 - PubMed
  11. Invest Ophthalmol Vis Sci. 2000 Oct;41(11):3437-43 - PubMed
  12. J Biol Chem. 1992 Nov 25;267(33):24082-9 - PubMed
  13. J Cell Biol. 1986 Mar;102(3):703-10 - PubMed
  14. J Cell Sci. 1991 Aug;99 ( Pt 4):797-807 - PubMed
  15. Crit Rev Oral Biol Med. 2000;11(3):279-303 - PubMed
  16. Invest Ophthalmol Vis Sci. 2005 Jan;46(1):1-7 - PubMed
  17. Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2634-43 - PubMed
  18. Invest Ophthalmol Vis Sci. 1986 Dec;27(12):1741-50 - PubMed
  19. Eye (Lond). 2000 Jun;14 ( Pt 3B):503-14 - PubMed
  20. Philos Trans R Soc Lond B Biol Sci. 2002 Feb 28;357(1418):207-17 - PubMed
  21. Invest Ophthalmol Vis Sci. 1992 Jun;33(7):2242-50 - PubMed
  22. Acta Physiol Scand. 1954;30(2-3):240-8 - PubMed
  23. Invest Ophthalmol Vis Sci. 1981 May;20(5):625-31 - PubMed
  24. Exp Eye Res. 1992 Nov;55(5):691-709 - PubMed
  25. Invest Ophthalmol Vis Sci. 2004 Nov;45(11):4023-34 - PubMed
  26. J Biol Chem. 2000 Mar 31;275(13):9410-7 - PubMed
  27. Ophthalmologe. 1993 Feb;90(1):66-72 - PubMed
  28. Invest Ophthalmol Vis Sci. 1997 May;38(6):1222-8 - PubMed
  29. Invest Ophthalmol Vis Sci. 1999 Sep;40(10):2235-41 - PubMed
  30. Exp Eye Res. 1975 Nov;21(5):417-31 - PubMed
  31. Exp Eye Res. 1992 Jun;54(6):879-83 - PubMed
  32. Invest Ophthalmol Vis Sci. 1982 Mar;22(3):319-29 - PubMed
  33. In Vitro Cell Dev Biol Anim. 1999 Mar;35(3):144-9 - PubMed
  34. Cancer Res. 2002 Sep 15;62(18):5358-64 - PubMed
  35. Invest Ophthalmol Vis Sci. 2001 Jul;42(8):1795-802 - PubMed
  36. Graefes Arch Clin Exp Ophthalmol. 2001 Feb;239(2):138-44 - PubMed
  37. Invest Ophthalmol Vis Sci. 1984 Mar;25(3):286-93 - PubMed
  38. Curr Eye Res. 1993 Jan;12(1):1-7 - PubMed
  39. Curr Eye Res. 1999 Nov;19(5):395-402 - PubMed
  40. Cell Res. 2005 Jul;15(7):483-94 - PubMed
  41. J Biol Chem. 1999 Jul 16;274(29):20444-9 - PubMed
  42. Invest Ophthalmol Vis Sci. 2007 May;48(5):2105-14 - PubMed
  43. J Pathol. 2003 Jul;200(4):488-99 - PubMed
  44. J Cell Biochem. 2004 Aug 1;92(5):1044-61 - PubMed
  45. IUBMB Life. 2002 Oct;54(4):187-94 - PubMed
  46. Adv Protein Chem. 2005;70:405-36 - PubMed
  47. Invest Ophthalmol. 1975 Mar;14(3):173-6 - PubMed
  48. Invest Ophthalmol Vis Sci. 2000 Sep;41(10):2984-90 - PubMed
  49. Invest Ophthalmol Vis Sci. 1991 Dec;32(13):3145-66 - PubMed
  50. Arch Ophthalmol. 2000 Jul;118(7):955-62 - PubMed
  51. Am J Ophthalmol. 1987 Jul 15;104(1):33-43 - PubMed
  52. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):794-801 - PubMed
  53. Curr Eye Res. 1990 Apr;9(4):363-9 - PubMed
  54. IUBMB Life. 2002 Oct;54(4):177-86 - PubMed
  55. Exp Eye Res. 1977;25 Suppl:65-116 - PubMed
  56. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Nov 8;208(1-3):33-47 - PubMed
  57. Exp Eye Res. 1977 Jan;24(1):71-80 - PubMed
  58. Br J Ophthalmol. 1996 May;80(5):389-93 - PubMed
  59. Invest Ophthalmol Vis Sci. 2005 Jan;46(1):214-22 - PubMed
  60. J Biol Chem. 2001 Jun 1;276(22):18947-52 - PubMed
  61. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S53-64 - PubMed
  62. Biochim Biophys Acta. 2002 Dec 19;1573(3):241-6 - PubMed
  63. J Cell Physiol. 2004 Oct;201(1):126-37 - PubMed
  64. Exp Eye Res. 1993 Jun;56(6):683-92 - PubMed
  65. Invest Ophthalmol. 1972 Jan;11(1):21-8 - PubMed
  66. Nat Rev Mol Cell Biol. 2001 Nov;2(11):793-805 - PubMed
  67. Nat Rev Mol Cell Biol. 2006 Apr;7(4):265-75 - PubMed
  68. Invest Ophthalmol Vis Sci. 2006 May;47(5):2011-20 - PubMed
  69. Invest Ophthalmol Vis Sci. 1994 Feb;35(2):486-94 - PubMed
  70. Int J Exp Pathol. 2000 Dec;81(6):373-90 - PubMed
  71. Invest Ophthalmol Vis Sci. 1989 Oct;30(10):2215-31 - PubMed
  72. Mech Dev. 2005 Jul;122(7-8):928-38 - PubMed
  73. Invest Ophthalmol Vis Sci. 1981 Oct;21(4):574-85 - PubMed
  74. Exp Eye Res. 2004 Nov;79(5):649-63 - PubMed
  75. Invest Ophthalmol Vis Sci. 1999 Jan;40(1):74-81 - PubMed
  76. Curr Eye Res. 2002 Nov;25(5):299-308 - PubMed
  77. Exp Eye Res. 2003 Nov;77(5):601-7 - PubMed
  78. Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3184-94 - PubMed
  79. Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2495-505 - PubMed
  80. Prog Retin Eye Res. 2003 Jul;22(4):435-63 - PubMed
  81. Exp Eye Res. 1986 May;42(5):443-55 - PubMed
  82. Invest Ophthalmol Vis Sci. 2003 May;44(5):1953-61 - PubMed
  83. Ophthalmology. 1983 Jul;90(7):758-65 - PubMed
  84. Invest Ophthalmol Vis Sci. 1997 Jan;38(1):83-91 - PubMed
  85. Exp Eye Res. 1989 Jan;48(1):139-47 - PubMed
  86. EMBO J. 1989 Jul;8(7):1939-46 - PubMed
  87. Invest Ophthalmol Vis Sci. 1996 Jan;37(1):104-13 - PubMed
  88. Biochem Biophys Res Commun. 2006 Apr 14;342(3):766-72 - PubMed
  89. Exp Eye Res. 2004 Jul;79(1):61-74 - PubMed
  90. J Glaucoma. 2004 Oct;13(5):421-38 - PubMed
  91. J Biol Chem. 2002 Dec 20;277(51):49120-6 - PubMed
  92. Invest Ophthalmol Vis Sci. 2006 May;47(5):1956-67 - PubMed
  93. Invest Ophthalmol Vis Sci. 2002 Apr;43(4):1068-76 - PubMed
  94. Arch Ophthalmol. 1997 Mar;115(3):375-83 - PubMed
  95. Exp Eye Res. 2003 Aug;77(2):181-8 - PubMed
  96. Matrix Biol. 2005 Sep;24(6):389-99 - PubMed
  97. Invest Ophthalmol Vis Sci. 2002 Jan;43(1):33-40 - PubMed
  98. Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2829-37 - PubMed
  99. Histol Histopathol. 2007 Oct;22(10):1077-84 - PubMed
  100. Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1491-9 - PubMed
  101. Biophys J. 2004 Oct;87(4):2828-37 - PubMed
  102. J Biol Chem. 2001 Mar 9;276(10):7422-30 - PubMed
  103. IUBMB Life. 2002 Oct;54(4):195-9 - PubMed
  104. Invest Ophthalmol Vis Sci. 2004 Jul;45(7):2246-54 - PubMed
  105. Invest Ophthalmol Vis Sci. 1996 Nov;37(12):2414-25 - PubMed
  106. Invest Ophthalmol Vis Sci. 2001 Jun;42(7):1505-13 - PubMed
  107. J Cell Biol. 1989 May;108(5):1945-53 - PubMed
  108. Ophthalmologica. 1997;211(3):126-39 - PubMed
  109. Invest Ophthalmol Vis Sci. 1996 Apr;37(5):795-804 - PubMed
  110. Trans Ophthalmol Soc U K. 1956;76:51-63 - PubMed
  111. Invest Ophthalmol Vis Sci. 1991 Jan;32(1):181-8 - PubMed
  112. Exp Eye Res. 2002 Feb;74(2):161-72 - PubMed
  113. Invest Ophthalmol Vis Sci. 2002 Jan;43(1):133-9 - PubMed
  114. Cell Motil Cytoskeleton. 2005 Feb;60(2):83-95 - PubMed
  115. Ophthalmology. 1991 May;98(5):692-700 - PubMed
  116. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5139-43 - PubMed
  117. Science. 1997 Jan 31;275(5300):668-70 - PubMed
  118. Mol Vis. 2006 Jul 12;12:774-90 - PubMed
  119. J Glaucoma. 2000 Oct;9(5):343-5 - PubMed
  120. J Biol Chem. 1995 Dec 1;270(48):29012-7 - PubMed
  121. Curr Opin Cell Biol. 2002 Oct;14(5):608-16 - PubMed
  122. Invest Ophthalmol Vis Sci. 1994 Jan;35(1):281-94 - PubMed
  123. Biochem J. 1999 Jun 15;340 ( Pt 3):693-701 - PubMed
  124. Am J Ophthalmol. 1972 May;73(5):760-89 - PubMed
  125. Invest Ophthalmol Vis Sci. 2005 Jan;46(1):223-34 - PubMed
  126. Exp Eye Res. 1990 Jul;51(1):55-63 - PubMed
  127. Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1191-200 - PubMed
  128. Curr Eye Res. 1989 Oct;8(10):1071-82 - PubMed
  129. Invest Ophthalmol Vis Sci. 1985 Jun;26(6):797-804 - PubMed
  130. J Biol Chem. 2002 Apr 19;277(16):13650-8 - PubMed
  131. Graefes Arch Clin Exp Ophthalmol. 1982;218(3):113-7 - PubMed
  132. Matrix Biol. 2003 Mar;22(1):25-33 - PubMed
  133. Invest Ophthalmol Vis Sci. 1995 Jun;36(7):1379-89 - PubMed
  134. Invest Ophthalmol Vis Sci. 1998 Apr;39(5):673-80 - PubMed
  135. Invest Ophthalmol Vis Sci. 1992 Apr;33(5):1670-5 - PubMed
  136. Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4181-7 - PubMed
  137. Int J Mol Med. 1998 Feb;1(2):339-46 - PubMed
  138. Invest Ophthalmol Vis Sci. 2000 Feb;41(2):352-61 - PubMed
  139. Semin Cell Dev Biol. 2001 Apr;12(2):117-25 - PubMed
  140. AMA Arch Ophthalmol. 1955 Aug;54(2):245-8 - PubMed
  141. Exp Eye Res. 2002 Sep;75(3):347-58 - PubMed
  142. Cell. 1988 May 6;53(3):383-90 - PubMed
  143. Invest Ophthalmol Vis Sci. 1996 Jun;37(7):1360-7 - PubMed
  144. Mol Vis. 2005 Apr 27;11:288-97 - PubMed
  145. Invest Ophthalmol Vis Sci. 2000 Jul;41(8):2059-66 - PubMed
  146. Invest Ophthalmol Vis Sci. 2006 Jan;47(1):226-34 - PubMed
  147. Arch Ophthalmol. 1992 Jan;110(1):110-7 - PubMed
  148. J Biol Chem. 1984 Mar 25;259(6):3955-61 - PubMed
  149. Exp Eye Res. 1994 Feb;58(2):181-7 - PubMed
  150. Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1164-72 - PubMed
  151. Exp Eye Res. 1971 Jan;11(1):116-21 - PubMed
  152. J Biol Chem. 2002 Feb 8;277(6):4565-72 - PubMed
  153. J Biol Chem. 2005 Feb 25;280(8):6915-22 - PubMed
  154. AMA Arch Ophthalmol. 1958 Oct;60(4 Part 1):523-33 - PubMed
  155. Curr Opin Ophthalmol. 2000 Apr;11(2):112-5 - PubMed
  156. J Cell Sci. 1992 Oct;103 ( Pt 2):445-51 - PubMed
  157. Invest Ophthalmol Vis Sci. 2007 Feb;48(2):715-26 - PubMed
  158. J Biol Chem. 1999 Jul 30;274(31):22053-9 - PubMed
  159. Graefes Arch Clin Exp Ophthalmol. 1984;221(5):199-206 - PubMed
  160. Invest Ophthalmol. 1970 Jan;9(1):42-52 - PubMed
  161. Invest Ophthalmol Vis Sci. 1997 Dec;38(13):2790-9 - PubMed
  162. Exp Eye Res. 2000 Apr;70(4):457-65 - PubMed
  163. FASEB J. 1993 Dec;7(15):1475-82 - PubMed
  164. Invest Ophthalmol Vis Sci. 1981 Oct;21(4):563-73 - PubMed
  165. Hum Mol Genet. 2002 May 15;11(11):1333-42 - PubMed
  166. Invest Ophthalmol Vis Sci. 1998 Jul;39(8):1361-71 - PubMed
  167. J Glaucoma. 1993 Summer;2(2):80-6 - PubMed
  168. Invest Ophthalmol Vis Sci. 1993 Nov;34(12):3386-95 - PubMed
  169. J Mol Biol. 2003 Jul 4;330(2):297-307 - PubMed
  170. Matrix Biol. 2006 Apr;25(3):175-84 - PubMed
  171. Nat Med. 2001 Mar;7(3):304-9 - PubMed
  172. J Cell Physiol. 1999 Aug;180(2):182-9 - PubMed
  173. Int Rev Cytol. 2001;207:113-50 - PubMed
  174. Exp Eye Res. 2006 Apr;82(4):545-57 - PubMed
  175. Arch Ophthalmol. 1998 May;116(5):633-43 - PubMed
  176. Invest Ophthalmol Vis Sci. 2002 Jan;43(1):151-61 - PubMed
  177. N Engl J Med. 1993 Apr 15;328(15):1097-106 - PubMed
  178. Curr Eye Res. 2001 Mar;22(3):235-44 - PubMed
  179. Curr Eye Res. 1998 Feb;17(2):211-7 - PubMed
  180. Arch Ophthalmol. 1963 Jun;69:783-801 - PubMed
  181. Mol Biol Cell. 2000 May;11(5):1499-507 - PubMed
  182. Curr Eye Res. 2003 Sep;27(3):165-73 - PubMed
  183. Nat Rev Mol Cell Biol. 2003 Jun;4(6):479-89 - PubMed
  184. Exp Eye Res. 1990 Dec;51(6):691-9 - PubMed
  185. J Cell Sci. 1999 Oct;112 ( Pt 20):3415-20 - PubMed
  186. Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5174-81 - PubMed
  187. Curr Opin Cell Biol. 2002 Oct;14(5):617-23 - PubMed
  188. Mol Vis. 2002 Mar 06;8:32-44 - PubMed
  189. Exp Eye Res. 1992 Apr;54(4):531-43 - PubMed
  190. Curr Eye Res. 1998 Mar;17(3):276-85 - PubMed
  191. Curr Eye Res. 1995 Jul;14(7):537-44 - PubMed
  192. Invest Ophthalmol Vis Sci. 2002 Dec;43(12):3691-7 - PubMed
  193. Cell. 1998 Jun 26;93(7):1159-70 - PubMed
  194. Invest Ophthalmol Vis Sci. 2004 Jan;45(1):153-8 - PubMed
  195. IUBMB Life. 2002 Oct;54(4):163-75 - PubMed
  196. J Cell Biol. 1992 Aug;118(4):979-90 - PubMed
  197. Exp Eye Res. 1994 Dec;59(6):723-7 - PubMed
  198. J Biol Chem. 2003 Sep 26;278(39):37698-704 - PubMed
  199. Invest Ophthalmol Vis Sci. 1995 Feb;36(2):478-89 - PubMed
  200. Curr Opin Ophthalmol. 1998 Apr;9(2):15-23 - PubMed
  201. Invest Ophthalmol Vis Sci. 2000 Jul;41(8):2229-38 - PubMed
  202. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):997-1007 - PubMed
  203. Invest Ophthalmol Vis Sci. 1991 Jan;32(1):160-71 - PubMed
  204. J Biol Chem. 2002 Mar 29;277(13):11050-7 - PubMed
  205. J Glaucoma. 1995 Jun;4(3):183-8 - PubMed
  206. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1974;192(2):89-104 - PubMed
  207. Am J Ophthalmol. 1974 Apr;77(4):565-72 - PubMed
  208. Invest Ophthalmol Vis Sci. 1998 Dec;39(13):2649-58 - PubMed
  209. Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4772-9 - PubMed
  210. AMA Arch Ophthalmol. 1958 Aug;60(2):290-4 - PubMed
  211. Curr Eye Res. 1997 May;16(5):412-21 - PubMed
  212. Surv Ophthalmol. 1996 Mar-Apr;40(5):379-90 - PubMed
  213. J Biol Chem. 2001 Jan 5;276(1):187-93 - PubMed
  214. Curr Eye Res. 1995 Aug;14(8):727-30 - PubMed
  215. J Muscle Res Cell Motil. 2002;23(5-6):581-96 - PubMed
  216. Nat Rev Mol Cell Biol. 2003 Dec;4(12):926-37 - PubMed
  217. Invest Ophthalmol Vis Sci. 1982 Nov;23(5):646-50 - PubMed
  218. Trends Cardiovasc Med. 2006 Aug;16(6):209-15 - PubMed
  219. Invest Ophthalmol Vis Sci. 2000 Feb;41(2):422-30 - PubMed
  220. J Struct Biol. 2006 Jun;154(3):312-26 - PubMed
  221. Acta Physiol Scand. 1955;33(2-3):257-90 - PubMed
  222. Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2857-68 - PubMed
  223. Invest Ophthalmol Vis Sci. 2002 Nov;43(11):3455-64 - PubMed
  224. J Biol Chem. 2001 Jan 12;276(2):1253-61 - PubMed
  225. Invest Ophthalmol Vis Sci. 2003 Feb;44(2):473-85 - PubMed
  226. EMBO J. 1992 Dec;11(12):4281-90 - PubMed
  227. Curr Eye Res. 1987 Aug;6(8):959-67 - PubMed
  228. Curr Opin Cell Biol. 2001 Oct;13(5):584-92 - PubMed
  229. Matrix Biol. 2001 Feb;20(1):37-51 - PubMed
  230. Prog Retin Eye Res. 1999 Jan;18(1):91-119 - PubMed
  231. Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4796-804 - PubMed
  232. Am J Ophthalmol. 1974 Apr;77(4):573-7 - PubMed
  233. Invest Ophthalmol Vis Sci. 1978 Mar;17(3):258-71 - PubMed
  234. Mol Vis. 2005 Aug 12;11:603-8 - PubMed
  235. Curr Eye Res. 1989 Dec;8(12):1233-40 - PubMed
  236. Exp Eye Res. 1997 Aug;65(2):177-90 - PubMed
  237. J Biol Chem. 2005 Jan 21;280(3):2116-25 - PubMed
  238. Invest Ophthalmol Vis Sci. 1981 Jul;21(1 Pt 1):52-72 - PubMed
  239. Invest Ophthalmol Vis Sci. 1994 Oct;35(11):3841-51 - PubMed
  240. Am J Ophthalmol. 1994 Jun 15;117(6):741-55 - PubMed
  241. Invest Ophthalmol Vis Sci. 2001 Apr;42(5):1029-37 - PubMed
  242. J Mol Med (Berl). 2007 Aug;85(8):825-36 - PubMed
  243. J Clin Invest. 2001 Aug;108(4):497-501 - PubMed
  244. Ann Ophthalmol. 1979 Jan;11(1):49-54 - PubMed
  245. J Cell Biol. 1986 Aug;103(2):393-404 - PubMed

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