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Konstantinova MF, Nekrasova TP, Nisman BKh. Temperaturnaia zavisimost' aktivnosti proteinkinaz A i C u variantov kletok neĭroblastomy myshi, geneticheski razlichaiushchikhsia po teploustoĭchivosti. [The temperature dependence of protein kinase A and C activity in variant mouse neuroblastoma cells differing genetically in their heat resistance]. Tsitologiia. 1991;33(12):54-8
Konstantinova, M. F., Nekrasova, T. P., & Nisman, B. K. h. (1991). Temperaturnaia zavisimost' aktivnosti proteinkinaz A i C u variantov kletok neĭroblastomy myshi, geneticheski razlichaiushchikhsia po teploustoĭchivosti. [The temperature dependence of protein kinase A and C activity in variant mouse neuroblastoma cells differing genetically in their heat resistance]. Tsitologiia, 33(12), 54-8.
Konstantinova, M F, et al. "Temperaturnaia zavisimost' aktivnosti proteinkinaz A i C u variantov kletok neĭroblastomy myshi, geneticheski razlichaiushchikhsia po teploustoĭchivosti." [The temperature dependence of protein kinase A and C activity in variant mouse neuroblastoma cells differing genetically in their heat resistance]. Tsitologiia vol. 33,12 (1991): 54-8.
Konstantinova MF, Nekrasova TP, Nisman BKh. Temperaturnaia zavisimost' aktivnosti proteinkinaz A i C u variantov kletok neĭroblastomy myshi, geneticheski razlichaiushchikhsia po teploustoĭchivosti. [The temperature dependence of protein kinase A and C activity in variant mouse neuroblastoma cells differing genetically in their heat resistance]. Tsitologiia. 1991;33(12):54-8. Russian. PMID: 1841458.
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Tsitologiia. 1991;33(12):54-8.

[The temperature dependence of protein kinase A and C activity in variant mouse neuroblastoma cells differing genetically in their heat resistance].

Tsitologiia

[Article in Russian]
M F Konstantinova, T P Nekrasova, B Kh Nisman

PMID: 1841458

Abstract

The ability of the mouse neuroblastoma cell line NTR to proliferate at 40 degrees C correlates with the position of the temperature optimum of protein kinases A and C activities in the region of higher temperatures compared to those for cells of the original line N18AI, and with higher thermostability of protein kinase A after its heating at various elevated temperatures. The found changes in protein kinases A and C in the cells of NTR line mean that the selection of variants, capable of growing at elevated temperatures, is accompanied with conformational protein changes.

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