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Barrios L, Caballín MR, Miró R, et al. Chromosomal instability in breast cancer patients. Hum Genet. 1991;88(1):39-41doi: 10.1007/BF00204926.
Barrios, L., Caballín, M. R., Miró, R., Fuster, C., Guedea, F., Subias, A., & Egozcue, J. (1991). Chromosomal instability in breast cancer patients. Human genetics, 88(1), 39-41. https://doi.org/10.1007/BF00204926
Barrios, L, et al. "Chromosomal instability in breast cancer patients." Human genetics vol. 88,1 (1991): 39-41. doi: https://doi.org/10.1007/BF00204926
Barrios L, Caballín MR, Miró R, Fuster C, Guedea F, Subias A, Egozcue J. Chromosomal instability in breast cancer patients. Hum Genet. 1991 Nov;88(1):39-41. doi: 10.1007/BF00204926. PMID: 1959924.
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Hum Genet. 1991 Nov;88(1):39-41. doi: 10.1007/BF00204926.

Chromosomal instability in breast cancer patients.

Human genetics

L Barrios, M R Caballín, R Miró, C Fuster, F Guedea, A Subias, J Egozcue

Affiliations

  1. Department de Biologia Cel.lular i Fisiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Spain.

PMID: 1959924 DOI: 10.1007/BF00204926

Abstract

We have carried out cytogenetic studies, using the G-banding technique, in peripheral blood lymphocytes of 10 patients affected by breast carcinoma. The frequency of aberrant metaphases (7.36%) is significantly different from that of our laboratory controls (3.76% of aberrant metaphases) but not from that detected in patients suffering from bladder cancer (10.64%) and Hodgkin's disease (11.03%), two conditions that have previously been described as chromosomally unstable. Our results suggest that breast carcinoma patients show a degree of chromosomal instability that could be related to a predisposition to neoplastic disease.

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