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Stull MA, Moser RP, Kransdorf MJ, et al. Magnetic resonance appearance of peripheral nerve sheath tumors. Skeletal Radiol. 1991;20(1):9-14doi: 10.1007/BF00243714.
Stull, M. A., Moser, R. P., Kransdorf, M. J., Bogumill, G. P., & Nelson, M. C. (1991). Magnetic resonance appearance of peripheral nerve sheath tumors. Skeletal radiology, 20(1), 9-14. https://doi.org/10.1007/BF00243714
Stull, M A, et al. "Magnetic resonance appearance of peripheral nerve sheath tumors." Skeletal radiology vol. 20,1 (1991): 9-14. doi: https://doi.org/10.1007/BF00243714
Stull MA, Moser RP, Kransdorf MJ, Bogumill GP, Nelson MC. Magnetic resonance appearance of peripheral nerve sheath tumors. Skeletal Radiol. 1991;20(1):9-14. doi: 10.1007/BF00243714. PMID: 1900374.
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Skeletal Radiol. 1991;20(1):9-14. doi: 10.1007/BF00243714.

Magnetic resonance appearance of peripheral nerve sheath tumors.

Skeletal radiology

M A Stull, R P Moser, M J Kransdorf, G P Bogumill, M C Nelson

Affiliations

  1. Department of Radiology, Georgetown University Medical Center, Washington, DC.

PMID: 1900374 DOI: 10.1007/BF00243714

Abstract

Magnetic resonance imaging (MRI) was used to evaluate 22 histologically proven peripheral nerve sheath tumors, approximately two-thirds of which arose in the lower extremity. The histologic distribution was as follows: 12 schwannomas, 7 neurofibromas, and 3 malignant peripheral nerve sheath tumors (2 of which occurred in patients with neurofibromatosis). Most lesions demonstrated an intermediate to moderately bright signal on T1-weighted images and were minimally inhomogeneous. All lesions were moderately bright on proton-density-weighted images and bright on T2-weighted images, again with variable inhomogeneity. The extent of the tumor was best assessed on proton-density- and T2-weighted images. Smooth margins were noted in 19 lesions. Of the 3 remaining lesions, 2 were malignant (but had been subjected to biopsy prior to MRI), and the other lesion was a plexiform neurofibroma. MRI accurately determined the relationship between the lesion and the adjacent neurovascular structures and muscles, thereby assisting surgical management. On MRI, 5 lesions demonstrated coexistent subtle muscle atrophy along the longitudinal axis of surrounding or distally innervated musculature. This latter finding, together with the presence of a tumor in the vicinity of a large nerve trunk, suggests a peripheral nerve sheath neoplasm.

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