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Hoffman R, Largiadèr F, Brütsch HP. Perioperative Thromboembolieprophylaxe mit niedermolekularen Heparin und postoperative Blutungskomplikation. [Perioperative prevention of thromboembolism with low molecular weight heparin and postoperative bleeding complications]. Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990;1179-84
Hoffman, R., Largiadèr, F., & Brütsch, H. P. (1990). Perioperative Thromboembolieprophylaxe mit niedermolekularen Heparin und postoperative Blutungskomplikation. [Perioperative prevention of thromboembolism with low molecular weight heparin and postoperative bleeding complications]. Langenbecks Archiv fur Chirurgie. Supplement II, Verhandlungen der Deutschen Gesellschaft fur Chirurgie. Deutsche Gesellschaft fur Chirurgie. Kongress, 1179-84.
Hoffman, R, et al. "Perioperative Thromboembolieprophylaxe mit niedermolekularen Heparin und postoperative Blutungskomplikation." [Perioperative prevention of thromboembolism with low molecular weight heparin and postoperative bleeding complications]. Langenbecks Archiv fur Chirurgie. Supplement II, Verhandlungen der Deutschen Gesellschaft fur Chirurgie. Deutsche Gesellschaft fur Chirurgie. Kongress vol. (1990): 1179-84.
Hoffman R, Largiadèr F, Brütsch HP. Perioperative Thromboembolieprophylaxe mit niedermolekularen Heparin und postoperative Blutungskomplikation. [Perioperative prevention of thromboembolism with low molecular weight heparin and postoperative bleeding complications]. Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990;1179-84. German. PMID: 1983509.
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Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990;1179-84.

[Perioperative prevention of thromboembolism with low molecular weight heparin and postoperative bleeding complications].

Langenbecks Archiv fur Chirurgie. Supplement II, Verhandlungen der Deutschen Gesellschaft fur Chirurgie. Deutsche Gesellschaft fur Chirurgie. Kongress

[Article in German]
R Hoffman, F Largiadèr, H P Brütsch

Affiliations

  1. Dep. Chirurgie, Universitätsspital, Zürich.

PMID: 1983509

Abstract

In three studies the effect and secondary effect of low molecular weight heparin (LMWH) were examined. Study 1: LMWH (Embolex-LM, n = 464) versus standard heparin (Liquemin, n = 452); Study 2: LMWH (Sandoparin, n = 298) versus standard heparin (n = 296). In the 3rd study controls of LMWH were performed in the clinic of visceral surgery, and the clinic of traumatology both. During these three studies all excluded patients who did not receive a thromboembolic prophylaxis were also examined. The first two studies showed no significant differences in the frequency of thromboembolic and bleeding complications. The bleeding complication was the same (3-6%) in the group of excluded patients. This is valid for study 3 too. In all studies the surgeon had an important influence on the frequency of bleeding complications.

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