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Liu PF, Zhu WH, Huang CM. Vaccines and photodynamic therapies for oral microbial-related diseases. Curr Drug Metab. 2009;10(1):90-4doi: 10.2174/138920009787048365.
Liu, P. F., Zhu, W. H., & Huang, C. M. (2009). Vaccines and photodynamic therapies for oral microbial-related diseases. Current drug metabolism, 10(1), 90-4. https://doi.org/10.2174/138920009787048365
Liu, Pei-Feng, et al. "Vaccines and photodynamic therapies for oral microbial-related diseases." Current drug metabolism vol. 10,1 (2009): 90-4. doi: https://doi.org/10.2174/138920009787048365
Liu PF, Zhu WH, Huang CM. Vaccines and photodynamic therapies for oral microbial-related diseases. Curr Drug Metab. 2009 Jan;10(1):90-4. doi: 10.2174/138920009787048365. PMID: 19149517; PMCID: PMC2776031.
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Curr Drug Metab. 2009 Jan;10(1):90-4. doi: 10.2174/138920009787048365.

Vaccines and photodynamic therapies for oral microbial-related diseases.

Current drug metabolism

Pei-Feng Liu, Wen-Hong Zhu, Chun-Ming Huang

Affiliations

  1. Division of Dermatology, Department of Medicine, University of California, San Diego, CA 92161, USA.

PMID: 19149517 PMCID: PMC2776031 DOI: 10.2174/138920009787048365

Abstract

The mouth is a favorable habitat for a great variety of bacteria. Microbial composition of dental plaque is the usual cause of various oral diseases in humans, including dental caries, periodontal disease and halitosis. In general, oral antibacterial agents such as antibiotics are commonly used to treat oral bacterial infection. Traditional periodontal surgery is painful and time-consuming. In addition, bacterial resistance and toxicity of antibiotics have become a global pandemic and unavoidable. Recently, vaccines for dental caries and periodontal disease have been developed and applied. Moreover, the use of photodynamic therapy has become an alternative to antibiotic drugs. The purpose of this article is to highlight the advantages of vaccine therapy and photodynamic therapy for oral microbial-related diseases compared to treatments with antimicrobial agents and traditional periodontal surgery.

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