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Yokogoshi Y, Yoshimoto K, Saito S. Loss of heterozygosity on chromosomes 1 and 11 in sporadic pheochromocytomas. Jpn J Cancer Res. 1990;81(6):632-8doi: 10.1111/j.1349-7006.1990.tb02620.x.
Yokogoshi, Y., Yoshimoto, K., & Saito, S. (1990). Loss of heterozygosity on chromosomes 1 and 11 in sporadic pheochromocytomas. Japanese journal of cancer research : Gann, 81(6), 632-8. https://doi.org/10.1111/j.1349-7006.1990.tb02620.x
Yokogoshi, Y, et al. "Loss of heterozygosity on chromosomes 1 and 11 in sporadic pheochromocytomas." Japanese journal of cancer research : Gann vol. 81,6 (1990): 632-8. doi: https://doi.org/10.1111/j.1349-7006.1990.tb02620.x
Yokogoshi Y, Yoshimoto K, Saito S. Loss of heterozygosity on chromosomes 1 and 11 in sporadic pheochromocytomas. Jpn J Cancer Res. 1990 Jun-Jul;81(6):632-8. doi: 10.1111/j.1349-7006.1990.tb02620.x. PMID: 1976119; PMCID: PMC6504067.
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Jpn J Cancer Res. 1990 Jun-Jul;81(6):632-8. doi: 10.1111/j.1349-7006.1990.tb02620.x.

Loss of heterozygosity on chromosomes 1 and 11 in sporadic pheochromocytomas.

Japanese journal of cancer research : Gann

Y Yokogoshi, K Yoshimoto, S Saito

Affiliations

  1. First Department of Internal Medicine, School of Medicine, University of Tokushima.

PMID: 1976119 PMCID: PMC6504067 DOI: 10.1111/j.1349-7006.1990.tb02620.x
Free PMC Article

Abstract

Molecular genetic analysis was performed with 20 oncogene probes and 32 polymorphic DNA probes on tumor DNA samples from seven pheochromocytomas; namely, one multiple endocrine neoplasia type 2B, and two familial and four sporadic pheochromocytomas. No amplification or rearrangement of the oncogenes was detected in any of the tumors. However, loss of heterozygosity on chromosome 1p, 11p or 11q was detected in these cases. In addition, a locus related to ETS1 was deleted in two of the sporadic tumors. These results suggest that pheochromocytomas may be genetically heterogeneous, and that inactivation of unknown genes on chromosome 1p, 11p or 11q may contribute to their development.

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References

  1. J Mol Biol. 1975 Nov 5;98(3):503-17 - PubMed
  2. Cancer Res. 1986 Oct;46(10):5101-5 - PubMed
  3. Science. 1989 Apr 7;244(4900):66-70 - PubMed
  4. Cancer Res. 1989 May 15;49(10):2716-21 - PubMed
  5. Proc Natl Acad Sci U S A. 1989 May;86(10):3753-7 - PubMed
  6. Hum Genet. 1989 Jun;82(3):287-8 - PubMed
  7. Nature. 1987 Aug 6-12;328(6130):527-8 - PubMed
  8. Nature. 1987 Aug 6-12;328(6130):528-30 - PubMed
  9. J Natl Cancer Inst. 1989 Mar 1;81(5):367-70 - PubMed
  10. Nature. 1985 Jul 25-31;316(6026):330-4 - PubMed
  11. Science. 1987 Apr 10;236(4798):175-80 - PubMed
  12. Semin Oncol. 1987 Sep;14(3):297-305 - PubMed
  13. Biochem J. 1987 Apr 15;243(2):313-27 - PubMed
  14. Science. 1987 Dec 11;238(4833):1539-45 - PubMed
  15. Nature. 1988 Sep 29;335(6189):400-2 - PubMed
  16. Proc Natl Acad Sci U S A. 1987 Sep;84(17):6131-5 - PubMed
  17. Cytogenet Cell Genet. 1987;46(1-4):390-566 - PubMed
  18. Proc Natl Acad Sci U S A. 1986 Mar;83(6):1792-6 - PubMed
  19. Nature. 1987 Aug 6-12;328(6130):524-6 - PubMed
  20. Cancer Genet Cytogenet. 1986 Feb 15;20(3-4):247-53 - PubMed
  21. Hum Pathol. 1982 Nov;13(11):1056 - PubMed
  22. Cancer Res. 1981 Nov;41(11 Pt 1):4678-86 - PubMed
  23. Cancer Res. 1981 Nov;41(11 Pt 1):4577-8 - PubMed
  24. Jinrui Idengaku Zasshi. 1982 Dec;27(4):335-40 - PubMed
  25. Anal Biochem. 1983 Jul 1;132(1):6-13 - PubMed
  26. N Engl J Med. 1976 Nov 11;295(20):1120-3 - PubMed
  27. Nucleic Acids Res. 1976 Sep;3(9):2303-8 - PubMed
  28. Birth Defects Orig Artic Ser. 1976;12(1):159-64 - PubMed

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