Display options
Cite
Pearlstein T, Steiner M. Premenstrual dysphoric disorder: burden of illness and treatment update. J Psychiatry Neurosci. 2008;33(4):291-301
Pearlstein, T., & Steiner, M. (2008). Premenstrual dysphoric disorder: burden of illness and treatment update. Journal of psychiatry & neuroscience : JPN, 33(4), 291-301.
Pearlstein, Teri, and Steiner, Meir. "Premenstrual dysphoric disorder: burden of illness and treatment update." Journal of psychiatry & neuroscience : JPN vol. 33,4 (2008): 291-301.
Pearlstein T, Steiner M. Premenstrual dysphoric disorder: burden of illness and treatment update. J Psychiatry Neurosci. 2008 Jul;33(4):291-301. PMID: 18592027; PMCID: PMC2440788.
Copy Download .nbib Format: NLM
Share it on

J Psychiatry Neurosci. 2008 Jul;33(4):291-301.

Premenstrual dysphoric disorder: burden of illness and treatment update.

Journal of psychiatry & neuroscience : JPN

Teri Pearlstein, Meir Steiner

Affiliations

  1. Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University and Women's Behavioral Health Program, Women and Infants Hospital, Providence, RI 02905, USA. [email protected]

PMID: 18592027 PMCID: PMC2440788

Abstract

Five percent of menstruating women have severe premenstrual symptoms and impairment of functioning defined as premenstrual dysphoric disorder (PMDD). Clinically significant premenstrual symptoms occur in at least an additional 20% of menstruating women. The diagnosis of PMDD should be confirmed by prospective symptom charting over 2 menstrual cycles to confirm the timing of the symptoms and to rule out other diagnoses. The burden of illness of PMDD includes disruption of parenting and partner relationships and decreased productivity in work roles. In addition, women with PMDD have increased use of health care services such as clinician visits and increased use of prescription medications and over-the-counter preparations. The etiology of PMDD is multifactorial. In particular, dysregulation of the serotonin and allopregnanolone systems is implicated. Several effective treatment options exist, including serotonergic antidepressant medications and an oral contraceptive that contains ethinyl estradiol and drosperinone. In addition, other hormones that suppress ovulation, anxiolytics, cognitive therapy, chasteberry and calcium may be helpful.

Keywords: contraceptives, oral; premenstrual syndrome; serotonin uptake inhibitors; treatment

References

  1. Clin Ther. 2002 Mar;24(3):417-33 - PubMed
  2. J Manipulative Physiol Ther. 1999 Nov-Dec;22(9):582-5 - PubMed
  3. J Int Med Res. 1988 Jul-Aug;16(4):270-9 - PubMed
  4. Int J Psychosom. 1994;41(1-4):53-60 - PubMed
  5. Can J Psychiatry. 2002 Nov;47(9):888-9 - PubMed
  6. J Clin Psychiatry. 2000 Feb;61(2):101-9 - PubMed
  7. Obstet Gynecol. 2008 May;111(5):1175-82 - PubMed
  8. J Am Coll Nutr. 2000 Feb;19(1):3-12 - PubMed
  9. J Womens Health (Larchmt). 2006 Jan-Feb;15(1):57-69 - PubMed
  10. J Reprod Med. 1987 Jun;32(6):400-4 - PubMed
  11. Arch Womens Ment Health. 2006 Jan;9(1):51-7 - PubMed
  12. J Affect Disord. 2007 Dec;104(1-3):37-44 - PubMed
  13. Acta Obstet Gynecol Scand. 1995 Nov;74(10):803-8 - PubMed
  14. Int J Psychiatry Med. 2003;33(3):295-7 - PubMed
  15. Hum Reprod. 2004 Sep;19(9):2152-5 - PubMed
  16. Arch Gen Psychiatry. 1990 Mar;47(3):270-5 - PubMed
  17. J Psychosom Obstet Gynaecol. 2000 Mar;21(1):9-15 - PubMed
  18. Br J Obstet Gynaecol. 1990 Sep;97(9):847-52 - PubMed
  19. J Affect Disord. 2002 Jul;70(2):125-32 - PubMed
  20. Depress Anxiety. 2002;15(1):48-51 - PubMed
  21. Med Care. 2002 Nov;40(11):1101-12 - PubMed
  22. Biol Psychiatry. 1999 Feb 1;45(3):313-20 - PubMed
  23. Psychopharmacol Bull. 2006;39(1):147-66 - PubMed
  24. Prim Care Companion J Clin Psychiatry. 2005;7(2):53-60 - PubMed
  25. N Engl J Med. 1998 Jan 22;338(4):209-16 - PubMed
  26. Neuropsychopharmacology. 1993 Sep;9(2):133-45 - PubMed
  27. BMJ. 1999 May 22;318(7195):1375-81 - PubMed
  28. J Womens Health Gend Based Med. 1999 Oct;8(8):1043-52 - PubMed
  29. Psychiatry Res. 1999 Jun 30;86(3):185-92 - PubMed
  30. J Psychosom Res. 2002 Sep;53(3):811-7 - PubMed
  31. J Clin Psychopharmacol. 2008 Apr;28(2):195-202 - PubMed
  32. Psychiatry Res. 1996 Nov 15;65(2):97-106 - PubMed
  33. Br J Nutr. 2005 May;93(5):731-9 - PubMed
  34. Am J Manag Care. 2005 Dec;11(16 Suppl):S492-7 - PubMed
  35. Neuroendocrinology. 2006;84(4):244-54 - PubMed
  36. Arch Womens Ment Health. 2003 Aug;6(3):203-9 - PubMed
  37. Am J Psychiatry. 1990 Dec;147(12):1634-6 - PubMed
  38. Contraception. 2001 Jul;64(1):51-8 - PubMed
  39. J Affect Disord. 2005 Apr;85(3):317-21 - PubMed
  40. Psychosom Med. 1992 Mar-Apr;54(2):167-81 - PubMed
  41. Arch Gen Psychiatry. 2002 Sep;59(9):851-8 - PubMed
  42. J Womens Health Gend Based Med. 1999 Jun;8(5):663-79 - PubMed
  43. Neurosci Lett. 2005 Mar 22;377(1):49-52 - PubMed
  44. Hum Psychopharmacol. 2003 Apr;18(3):191-5 - PubMed
  45. Arch Womens Ment Health. 2006 Jan;9(1):1-14 - PubMed
  46. J Womens Health Gend Based Med. 2001 Jul-Aug;10(6):561-9 - PubMed
  47. J Womens Health. 1998 Nov;7(9):1157-65 - PubMed
  48. Psychoneuroendocrinology. 2003 Apr;28(3):446-58 - PubMed
  49. J Obstet Gynaecol. 1997 Jan;17(1):76-9 - PubMed
  50. Postgrad Med. 2001 Mar;(Spec No):1-107 - PubMed
  51. J Obstet Gynecol Neonatal Nurs. 1999 Mar-Apr;28(2):165-74 - PubMed
  52. Eur Neuropsychopharmacol. 2002 Apr;12(2):129-34 - PubMed
  53. Biol Psychiatry. 2007 Oct 15;62(8):925-33 - PubMed
  54. Psychiatry Res. 2006 Dec 1;148(2-3):185-93 - PubMed
  55. Pharmacol Biochem Behav. 2006 Aug;84(4):656-66 - PubMed
  56. J Psychosom Res. 1998 Oct;45(4):307-18 - PubMed
  57. Arch Womens Ment Health. 2004 Feb;7(1):37-47 - PubMed
  58. Obstet Gynecol. 1993 Dec;82(6):906-11 - PubMed
  59. Ann N Y Acad Sci. 2003 Nov;997:330-40 - PubMed
  60. Contraception. 1992 Sep;46(3):253-68 - PubMed
  61. Front Neuroendocrinol. 2006 Jul;27(2):210-6 - PubMed
  62. Obstet Gynecol. 1990 Apr;75(4):649-55 - PubMed
  63. Psychoneuroendocrinology. 2003 Aug;28 Suppl 3:55-99 - PubMed
  64. Neuropsychopharmacology. 2007 Jan;32(1):153-61 - PubMed
  65. J Clin Psychopharmacol. 2006 Apr;26(2):198-202 - PubMed
  66. CNS Drugs. 2001;15(4):277-85 - PubMed
  67. Int Clin Psychopharmacol. 1993 Summer;8(2):95-102 - PubMed
  68. J Affect Disord. 2008 May;108(1-2):87-94 - PubMed
  69. Obstet Gynecol. 1986 Sep;68(3):395-8 - PubMed
  70. J Occup Environ Med. 2004 Jul;46(7):649-56 - PubMed
  71. J Clin Psychopharmacol. 1997 Aug;17(4):261-6 - PubMed
  72. Obstet Gynecol. 1988 Sep;72(3 Pt 1):332-6 - PubMed
  73. Fertil Steril. 2001 Feb;75(2):380-4 - PubMed
  74. Obstet Gynecol. 1995 Oct;86(4 Pt 1):520-8 - PubMed
  75. Arch Fam Med. 1999 Jul-Aug;8(4):328-32 - PubMed
  76. Cochrane Database Syst Rev. 2002;(4):CD001396 - PubMed
  77. J Reprod Med. 2003 Jul;48(7):515-24 - PubMed
  78. J Clin Psychiatry. 1997 Sep;58(9):399-402 - PubMed
  79. Biol Psychiatry. 2003 Oct 1;54(7):757-62 - PubMed
  80. Am J Obstet Gynecol. 1990 Jan;162(1):99-105 - PubMed
  81. Contraception. 2005 Apr;71(4):304-5 - PubMed
  82. J Altern Complement Med. 2004 Jun;10(3):456-62 - PubMed
  83. Int J Gynaecol Obstet. 2002 Jun;77(3):253-4 - PubMed
  84. Am J Obstet Gynecol. 2003 May;188(5 Suppl):S56-65 - PubMed
  85. Am J Obstet Gynecol. 2006 Nov;195(5):1311-9 - PubMed
  86. Lancet. 1989 Apr 8;1(8641):777 - PubMed
  87. Obstet Gynecol. 2002 Sep;100(3):435-44 - PubMed
  88. Semin Reprod Endocrinol. 1997 Feb;15(1):55-68 - PubMed
  89. J Affect Disord. 2005 Apr;85(3):275-82 - PubMed
  90. JAMA. 1995 Jul 5;274(1):51-7 - PubMed
  91. Neuropsychopharmacology. 1995 Apr;12(2):167-76 - PubMed
  92. Obstet Gynecol. 1994 Sep;84(3):379-85 - PubMed
  93. Psychosom Med. 1999 Sep-Oct;61(5):676-97 - PubMed
  94. BJOG. 2008 Mar;115(4):515-9 - PubMed
  95. Arch Gen Psychiatry. 1999 Oct;56(10):932-9 - PubMed
  96. Biol Psychiatry. 2006 Feb 15;59(4):327-33 - PubMed
  97. Harv Rev Psychiatry. 1996 Nov-Dec;4(4):200-7 - PubMed
  98. Obstet Gynecol. 1991 Aug;78(2):177-81 - PubMed
  99. Arch Womens Ment Health. 2006 Jan;9(1):41-9 - PubMed
  100. J Clin Psychiatry. 1991 Jul;52(7):290-3 - PubMed
  101. J Clin Psychopharmacol. 1998 Oct;18(5):390-8 - PubMed
  102. Psychopharmacology (Berl). 1990;102(3):414-6 - PubMed
  103. Obstet Gynecol. 2005 Sep;106(3):492-501 - PubMed
  104. Psychoneuroendocrinology. 2003 Aug;28 Suppl 3:1-23 - PubMed
  105. Psychol Med. 2002 Jan;32(1):119-32 - PubMed
  106. Obstet Gynecol. 1992 Sep;80(3 Pt 1):339-44 - PubMed
  107. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003415 - PubMed
  108. Menopause. 2002 Jul-Aug;9(4):236-41 - PubMed
  109. J Clin Psychiatry. 2006 Oct;67(10):1624-32 - PubMed
  110. Res Nurs Health. 1999 Dec;22(6):496-511 - PubMed
  111. Neuropsychopharmacology. 1997 May;16(5):346-56 - PubMed
  112. Contraception. 2005 Dec;72(6):414-21 - PubMed
  113. J Clin Psychiatry. 2005 Jun;66(6):769-73 - PubMed
  114. Psychoneuroendocrinology. 2006 May;31(4):415-27 - PubMed
  115. JAMA. 1997 Sep 24;278(12):983-8 - PubMed
  116. Lancet. 2000 Sep 30;356(9236):1131-6 - PubMed
  117. CNS Drugs. 2006;20(7):523-47 - PubMed
  118. Obstet Gynecol Surv. 1983 Nov;38(11):643-6 - PubMed
  119. Am J Obstet Gynecol. 2005 Aug;193(2):352-60 - PubMed
  120. J Affect Disord. 1988 Sep-Oct;15(2):141-7 - PubMed
  121. J Psychosom Res. 1992 Apr;36(3):257-66 - PubMed
  122. Obstet Gynecol. 2001 Nov;98(5 Pt 1):737-44 - PubMed
  123. J Clin Psychiatry. 2001 May;62(5):337-42 - PubMed
  124. Am J Obstet Gynecol. 1990 Jan;162(1):105-9 - PubMed
  125. CNS Drugs. 2003;17(5):325-42 - PubMed
  126. Psychosom Med. 2001 Sep-Oct;63(5):822-9 - PubMed
  127. Am J Obstet Gynecol. 2001 Jul;185(1):227-35 - PubMed
  128. Neuropsychopharmacology. 2001 Nov;25(5 Suppl):S102-8 - PubMed
  129. J Holist Nurs. 1993 Sep;11(3):286-94 - PubMed
  130. Arch Gynecol Obstet. 2002 Nov;267(1):23-6 - PubMed
  131. Int J Gynaecol Obstet. 2007 Jan;96(1):43-4 - PubMed
  132. J Clin Psychiatry. 1998 Feb;59(2):76-80 - PubMed
  133. Psychosom Med. 2004 Sep-Oct;66(5):707-13 - PubMed
  134. Depress Anxiety. 2007;24(7):495-517 - PubMed
  135. J Psychosom Res. 1992 Dec;36(8):787-95 - PubMed
  136. Reprod Toxicol. 2003 Mar-Apr;17(2):137-52 - PubMed
  137. J Affect Disord. 2007 Sep;102(1-3):159-76 - PubMed
  138. Am J Obstet Gynecol. 2006 Nov;195(5):1254-9 - PubMed
  139. Arch Womens Ment Health. 2003 Feb;6(1):23-41 - PubMed
  140. Arch Gen Psychiatry. 1993 Jun;50(6):467-73 - PubMed
  141. BMJ. 2001 Oct 6;323(7316):776-80 - PubMed
  142. BJOG. 2004 Jun;111(6):585-93 - PubMed
  143. Psychoneuroendocrinology. 1995;20(2):193-209 - PubMed
  144. Eur J Obstet Gynecol Reprod Biol. 1997 Jun;73(2):167-70 - PubMed
  145. Am J Obstet Gynecol. 2003 Dec;189(6):1523-30 - PubMed
  146. BJOG. 2000 Jul;107(7):870-6 - PubMed
  147. J Affect Disord. 1999 Jun;53(3):269-73 - PubMed
  148. J Clin Psychiatry. 2001 Sep;62(9):688-93 - PubMed
  149. Compr Ther. 2001 Spring;27(1):65-71 - PubMed
  150. Altern Med Rev. 2003 May;8(2):171-9 - PubMed
  151. Acta Psychiatr Scand. 2001 Aug;104(2):110-6 - PubMed
  152. Acta Psychiatr Scand. 1992 Jan;85(1):39-47 - PubMed
  153. Psychiatry Res. 2005 Mar 30;134(1):27-36 - PubMed
  154. J Psychosom Obstet Gynaecol. 2002 Sep;23(3):193-9 - PubMed
  155. Obstet Gynecol. 2002 Dec;100(6):1219-29 - PubMed
  156. Psychiatr Clin North Am. 1998 Sep;21(3):577-90 - PubMed
  157. J Midwifery Womens Health. 2006 Nov-Dec;51(6):402-9 - PubMed
  158. Psychiatry Res. 2006 Mar 31;146(2):107-16 - PubMed
  159. Psychopharmacology (Berl). 2006 Jun;186(3):351-61 - PubMed
  160. Obstet Gynecol. 1987 Jul;70(1):37-43 - PubMed
  161. Obstet Gynecol. 2002 Jun;99(6):1014-24 - PubMed
  162. Gynecol Endocrinol. 1999 Feb;13(1):48-55 - PubMed
  163. Pharmacoeconomics. 2005;23(5):433-44 - PubMed
  164. Sports Med. 2002;32(12):741-60 - PubMed
  165. N Engl J Med. 1995 Jun 8;332(23):1529-34 - PubMed
  166. Gynecol Endocrinol. 2006 Aug;22(8):411-5 - PubMed
  167. Am J Obstet Gynecol. 2005 Sep;193(3 Pt 1):658-61 - PubMed
  168. J Occup Environ Med. 2005 Jan;47(1):26-33 - PubMed
  169. J Affect Disord. 1995 Jan 11;33(1):57-63 - PubMed
  170. Am J Obstet Gynecol. 1999 Jan;180(1 Pt 1):18-23 - PubMed
  171. Psychol Med. 2005 May;35(5):683-92 - PubMed
  172. J Clin Psychiatry. 2000;61 Suppl 12:17-21 - PubMed
  173. Am J Obstet Gynecol. 1998 Aug;179(2):444-52 - PubMed
  174. Am J Psychiatry. 2004 Feb;161(2):343-51 - PubMed
  175. Psychopharmacology (Berl). 2001 May;155(3):292-8 - PubMed
  176. Psychol Med. 2002 Jan;32(1):25-38 - PubMed
  177. J Womens Health Gend Based Med. 2000 Sep;9(7):757-68 - PubMed
  178. Am J Manag Care. 2005 Dec;11(16 Suppl):S480-91 - PubMed
  179. Psychiatry Clin Neurosci. 2004 Apr;58(2):186-90 - PubMed
  180. Am J Psychiatry. 1997 Dec;154(12):1741-6 - PubMed
  181. Treat Endocrinol. 2006;5(4):251-6 - PubMed

Substances

MeSH terms

Publication Types