Acta Otolaryngol. 1992;112(2):322-7. doi: 10.1080/00016489.1992.11665426.

Problems in alloplastic middle ear reconstruction.

Acta oto-laryngologica

A W Blayney, K R Williams, J P Erre, T H Lesser, M Portmann

PMID: 1605000 DOI: 10.1080/00016489.1992.11665426

Abstract

Alloplastic materials have been used in middle ear reconstruction since 1952. Biologically, biomaterials and specifically ceramics can be defined as being bioinert, bioactive or biodegradable; these terms being descriptive of the biochemical response provoked by the material in the host tissue. Various ceramics, carbons and polymers and their reactions have been studied by the author and his colleagues over the past 5 years utilising animal implantation and fibroblast culture studies aligned with experience from clinical usage. The qualities of the ideal alloplastic implant namely: biocompatibility, stabilisation and incorporation, the consistency of the implant and bioactive bonding and the biofunctionality or mechanics, are applied to the materials currently available. No single alloplastic material fulfills all criteria, the problems encountered in relation to the biomaterials are reported. A better understanding of the microstresses, fatigue and microfractures is necessary, before the ideal alloplastic biomaterial becomes available.

Cited by

Substances

• Biocompatible Materials

MeSH terms

• Animals
• Biocompatible Materials*
• Materials Testing*
• Microscopy, Electron, Scanning
• Ossicular Prosthesis*
• Prosthesis Design
• Prosthesis Failure
• Rats

Publication Types

• Comparative Study
• Journal Article

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