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Kossii NV, Khomenko IS, Gergert VIa. Lechenie immunodefitsitnykh sostoianiĭ, vyzvannykh perenesennoĭ virusnoĭ infektsieĭ, otechestvennym immunomoduliatorom kemantanom u bol'nykh tuberkulezom legkikh. [Treatment of immunodeficient conditions caused by viral infection with the Soviet immunomodulator kemantan in patients with pulmonary tuberculosis]. Probl Tuberk. 1991;(6):23-6
Kossii, N. V., Khomenko, I. S., & Gergert, V. I. a. (1991). Lechenie immunodefitsitnykh sostoianiĭ, vyzvannykh perenesennoĭ virusnoĭ infektsieĭ, otechestvennym immunomoduliatorom kemantanom u bol'nykh tuberkulezom legkikh. [Treatment of immunodeficient conditions caused by viral infection with the Soviet immunomodulator kemantan in patients with pulmonary tuberculosis]. Problemy tuberkuleza, (6), 23-6.
Kossii, N V, et al. "Lechenie immunodefitsitnykh sostoianiĭ, vyzvannykh perenesennoĭ virusnoĭ infektsieĭ, otechestvennym immunomoduliatorom kemantanom u bol'nykh tuberkulezom legkikh." [Treatment of immunodeficient conditions caused by viral infection with the Soviet immunomodulator kemantan in patients with pulmonary tuberculosis]. Problemy tuberkuleza vol. ,6 (1991): 23-6.
Kossii NV, Khomenko IS, Gergert VIa. Lechenie immunodefitsitnykh sostoianiĭ, vyzvannykh perenesennoĭ virusnoĭ infektsieĭ, otechestvennym immunomoduliatorom kemantanom u bol'nykh tuberkulezom legkikh. [Treatment of immunodeficient conditions caused by viral infection with the Soviet immunomodulator kemantan in patients with pulmonary tuberculosis]. Probl Tuberk. 1991;(6):23-6. Russian. PMID: 1780303.
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Probl Tuberk. 1991;(6):23-6.

[Treatment of immunodeficient conditions caused by viral infection with the Soviet immunomodulator kemantan in patients with pulmonary tuberculosis].

Problemy tuberkuleza

[Article in Russian]
N V Kossii, I S Khomenko, V Ia Gergert

PMID: 1780303

Abstract

Observation of 219 patients with pulmonary tuberculosis was made to study the effect of acute respiratory viral infection (ARVI) on the course of the disease. The affected were divided into 2 groups: 136 subjects who had ARVI and 83 persons who did not have it during their stay at a hospital. Patients with infiltrative pulmonary tuberculosis, and young and middle-aged men were prevalent in both groups. It was found that ARVI promoted the aggravation of a specific process in the lungs in 19.1 per cent of the patients. Keeping in mind a large proportion of aggravations and low immunologic indices as a consequence of ARVI, 14 patients were put on kemantan. Study of the immune status of the patients who had ARVI and received kemantan demonstrated a significant increase in the formation of blasts and the concentration of T cells whose functional activity tended to rise. At the same time the above-mentioned indices remained intact or tended to drop in patients receiving no kemantan. The Soviet immunomodulator kemantan is recommended for a combined treatment of the pulmonary tuberculosis patients who had intercurrent viral infection to stimulate cellular immune defences and prevent an aggravation of the specific process.

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