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Medvedeva NA, Kuznetsova LV, Medvedev OS. Narushenie simpaticheskoĭ reguliatsii funktsiĭ serdechno-sosudistoĭ sistemy u krys so streptozototsinovym diabetom. [Disordered sympathetic regulation of the functions of the cardiovascular system in rats with streptozotocin diabetes]. Biull Eksp Biol Med. 1991;112(11):462-5
Medvedeva, N. A., Kuznetsova, L. V., & Medvedev, O. S. (1991). Narushenie simpaticheskoĭ reguliatsii funktsiĭ serdechno-sosudistoĭ sistemy u krys so streptozototsinovym diabetom. [Disordered sympathetic regulation of the functions of the cardiovascular system in rats with streptozotocin diabetes]. Biulleten' eksperimental'noi biologii i meditsiny, 112(11), 462-5.
Medvedeva, N A, et al. "Narushenie simpaticheskoĭ reguliatsii funktsiĭ serdechno-sosudistoĭ sistemy u krys so streptozototsinovym diabetom." [Disordered sympathetic regulation of the functions of the cardiovascular system in rats with streptozotocin diabetes]. Biulleten' eksperimental'noi biologii i meditsiny vol. 112,11 (1991): 462-5.
Medvedeva NA, Kuznetsova LV, Medvedev OS. Narushenie simpaticheskoĭ reguliatsii funktsiĭ serdechno-sosudistoĭ sistemy u krys so streptozototsinovym diabetom. [Disordered sympathetic regulation of the functions of the cardiovascular system in rats with streptozotocin diabetes]. Biull Eksp Biol Med. 1991 Nov;112(11):462-5. Russian. PMID: 1810476.
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Biull Eksp Biol Med. 1991 Nov;112(11):462-5.

[Disordered sympathetic regulation of the functions of the cardiovascular system in rats with streptozotocin diabetes].

Biulleten' eksperimental'noi biologii i meditsiny

[Article in Russian]
N A Medvedeva, L V Kuznetsova, O S Medvedev

PMID: 1810476

Abstract

The effect of sympathomimetic tyramine on the systemic and regional hemodynamic parameters was studied by the radioactive microsphere technique in experiments on conscious streptozotocin-diabetic and age-matched control rats. The dose of tyramine required for blood pressure elevation on 15-20 mm Hg was 5.6 times as large in diabetic rats as compared to control animals. It was suggested that sympathetic neuropathy may play the role in the development of the cardiovascular alterations in streptozotocin-diabetic rats.

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